Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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G121425-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $91.90 | |
G121425-5g | 5g | In stock | $251.90 | |
G121425-10g | 10g | In stock | $403.90 | |
G121425-25g | 25g | In stock | $807.90 | |
G121425-100g | 100g | In stock | $2,262.90 | |
G121425-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $7,920.90 |
Synonyms | Glycyl-L-tyrosine|658-79-7|Gly-Tyr|N-Glycyl-L-tyrosine|Glycyltyrosine|H-Gly-Tyr-OH|L-Tyrosine, glycyl-|glycyl-tyrosine|(S)-2-(2-Aminoacetamido)-3-(4-hydroxyphenyl)propanoic acid|(2S)-2-[(2-aminoacetyl)amino]-3-(4-hydroxyphenyl)propanoic acid|Glycyl-L-tyro |
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Specifications & Purity | ≥98% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | (2S)-2-[(2-aminoacetyl)amino]-3-(4-hydroxyphenyl)propanoic acid |
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INCHI | InChI=1S/C11H14N2O4/c12-6-10(15)13-9(11(16)17)5-7-1-3-8(14)4-2-7/h1-4,9,14H,5-6,12H2,(H,13,15)(H,16,17)/t9-/m0/s1 |
InChi Key | XBGGUPMXALFZOT-VIFPVBQESA-N |
Canonical SMILES | C1=CC(=CC=C1CC(C(=O)O)NC(=O)CN)O |
Isomeric SMILES | C1=CC(=CC=C1C[C@@H](C(=O)O)NC(=O)CN)O |
WGK Germany | 3 |
Alternate CAS | 207300-83-2 |
PubChem CID | 92829 |
Molecular Weight | 238.24 (as Anhydrous) |
Beilstein | 2700715 |
Reaxy-Rn | 2700715 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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H2420537 | Certificate of Analysis | Aug 08, 2024 | G121425 |
H2420538 | Certificate of Analysis | Aug 08, 2024 | G121425 |
H2420539 | Certificate of Analysis | Aug 08, 2024 | G121425 |
H2420544 | Certificate of Analysis | Aug 08, 2024 | G121425 |
H2406438 | Certificate of Analysis | Jul 17, 2024 | G121425 |
F2009062 | Certificate of Analysis | Apr 03, 2024 | G121425 |
K1511058 | Certificate of Analysis | Jul 17, 2023 | G121425 |
H1930052 | Certificate of Analysis | Jun 08, 2023 | G121425 |
C2219270 | Certificate of Analysis | Feb 24, 2022 | G121425 |
C2219271 | Certificate of Analysis | Feb 24, 2022 | G121425 |
C2219272 | Certificate of Analysis | Feb 24, 2022 | G121425 |
C2219302 | Certificate of Analysis | Feb 24, 2022 | G121425 |
D1823058 | Certificate of Analysis | Feb 23, 2022 | G121425 |
D1823059 | Certificate of Analysis | Feb 23, 2022 | G121425 |
Specific Rotation[α] | 47.5° |
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Melt Point(°C) | 282 °C |
WGK Germany | 3 |
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Reaxy-Rn | 2700715 |
1. Vig BS, Stouch TR, Timoszyk JK, Quan Y, Wall DA, Smith RL, Faria TN. (2006) Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding.. J Med Chem, 49 (12): (3636-44). [PMID:16759105] |
2. L Cynober,F Ziegler,C Coudray-Lucas,F Bonnet,J Agneray,O G Ekindjian,G Nitenberg. (1989-05-13) Parenteral peptide supplements after major surgery.. Lancet (London, England), 1 ((8646)): (1085-1086). [PMID:2566039] |
3. S Albers,J Wernerman,P Stehle,E Vinnars,P Fürst. (1989-06-01) Availability of amino acids supplied by constant intravenous infusion of synthetic dipeptides in healthy man.. Clinical science (London, England : 1979), 76 ((6)): (643-648). [PMID:2736882] |
4. J K Park,S J Cho,S Lee,K S Kim,D H Kim. (1995-04-01) Conformational energies of substrates and inhibitors for carboxypeptidase A: stereoelectronic effect.. Journal of biomolecular structure & dynamics, 12 ((5)): (1033-1040). [PMID:7626238] |
5. W Druml,W Hübl,E Roth,H Lochs. (1995-04-01) Utilization of tyrosine-containing dipeptides and N-acetyl-tyrosine in hepatic failure.. Hepatology (Baltimore, Md.), 21 ((4)): (923-928). [PMID:7705801] |
6. C Goeters,N Mertes,M Kuhmann,V Lange,K H Dietl,P Lawin. (1994-05-01) [Safety and tolerance of a new dipeptide-containing amino acid solution DP-Gln 20 versus a conventional amino acid solution Vamin 18EF in patients after elective colon surgery].. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 29 ((3)): (146-149). [PMID:8043714] |
7. P Chen,A Hussain,H H Tai,L W Dittert. (1994-05-15) An improved method of radioiodination with chloramine T.. Analytical biochemistry, 219 ((1)): (159-161). [PMID:8059946] |
8. E C Meng,D A Gschwend,J M Blaney,I D Kuntz. (1993-11-01) Orientational sampling and rigid-body minimization in molecular docking.. Proteins, 17 ((3)): (266-278). [PMID:8272425] |
9. S Himmelseher,E Pfenninger,P Herrmann. (1996-07-01) Cerebrospinal and plasma amino acid concentrations after administration of i.v. glycyl-glutamine and glycyl-tyrosine containing amino acid solutions in humans.. JPEN. Journal of parenteral and enteral nutrition, 20 ((4)): (281-286). [PMID:8865110] |
10. J D House,P B Pencharz,R O Ball. (1997-04-01) Tyrosine kinetics and requirements during total parenteral nutrition in the neonatal piglet: the effect of glycyl-L-tyrosine supplementation.. Pediatric research, 41 ((4 Pt 1)): (575-583). [PMID:9098863] |
11. E A Liechty,D W Boyle,H Moorehead,L Auble,S C Denne. (1999-06-04) Aromatic amino acids are utilized and protein synthesis is stimulated during amino acid infusion in the ovine fetus.. The Journal of nutrition, 129 ((6)): (1161-1166). [PMID:10356081] |
12. M Miyashita,R Matsunaga,Y Seyama,S Yamashita. (1999-10-08) [Studies on iodinated compounds. X. Isolation and purification of iodoglycyltyrosines].. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 119 ((9)): (681-687). [PMID:10511819] |
13. C E Sänger-van de Griend. (1999-12-23) Enantiomeric separation of glycyl dipeptides by capillary electrophoresis with cyclodextrins as chiral selectors.. Electrophoresis, 20 ((17)): (3417-3424). [PMID:10608709] |
14. S A Roberts,R O Ball,A M Moore,R M Filler,P B Pencharz. (2001-01-03) The effect of graded intake of glycyl-L-tyrosine on phenylalanine and tyrosine metabolism in parenterally fed neonates with an estimation of tyrosine requirement.. Pediatric research, 49 ((1)): (111-119). [PMID:11134500] |
15. Martin G Schmid,Maria Hölbling,Nikola Schnedlitz,Gerald Gübitz. (2004-11-25) Enantioseparation of dipeptides and tripeptides by micro-HPLC comparing teicoplanin and teicoplanin aglycone as chiral selectors.. Journal of biochemical and biophysical methods, 61 ((1-2)): (1-10). [PMID:15560917] |
16. Christina Gatschelhofer,Martin G Schmid,Karin Schreiner,Thomas R Pieber,Frank M Sinner,Gerald Gübitz. (2006-03-25) Enantioseparation of glycyl-dipeptides by CEC using particle-loaded monoliths prepared by ring-opening metathesis polymerization (ROMP).. Journal of biochemical and biophysical methods, 69 ((1-2)): (67-77). [PMID:16556463] |
17. Martin G Schmid,Karin Schreiner,Daniela Reisinger,Gerald Gübitz. (2006-08-10) Fast chiral separation by ligand-exchange HPLC using a dynamically coated monolithic column.. Journal of separation science, 29 ((10)): (1470-1475). [PMID:16894792] |
18. Heike Hödl,Martin G Schmid,Gerald Gübitz. (2008-06-24) Chiral separation of amino acids and glycyl dipeptides by chiral ligand-exchange capillary electrophoresis comparing Cu(II), Co(II), Ni(II) and Zn(II) complexes of three different sugar acids.. Journal of chromatography. A, 1204 ((2)): (210-218). [PMID:18571185] |
19. Takeharu Nakahara,Katsutoshi Sugimoto,Atsushi Sano,Hitomi Yamaguchi,Hiroshi Katayama,Riichiro Uchida. (2012-03-16) Antihypertensive mechanism of a peptide-enriched soy sauce-like seasoning: the active constituents and its suppressive effect on renin-angiotensin-aldosterone system.. Journal of food science, 76 ((8)): (H201-H206). [PMID:22417592] |
20. Sidsel Frølund,Louise Langthaler,Morten A Kall,René Holm,Carsten Uhd Nielsen. (2012-08-03) Intestinal drug transport via the proton-coupled amino acid transporter PAT1 (SLC36A1) is inhibited by Gly-X(aa) dipeptides.. Molecular pharmaceutics, 9 ((9)): (2761-2769). [PMID:22853447] |
21. Yuanzhong Yang,Reinhard I Boysen,Jamil Chowdhury,Asif Alam,Milton T W Hearn. (2015-04-22) Analysis of peptides and protein digests by reversed phase high performance liquid chromatography-electrospray ionisation mass spectrometry using neutral pH elution conditions.. Analytica chimica acta, 872 (84-94). [PMID:25892073] |
22. Wentao Wang,Xing Xiao,Jia Chen,Li Jia. (2015-08-13) Carboxyl modified magnetic nanoparticles coated open tubular column for capillary electrochromatographic separation of biomolecules.. Journal of chromatography. A, 1411 (92-100). [PMID:26265004] |
23. L J Wykes,J D House,R O Ball,P B Pencharz. (1994-11-01) Aromatic amino acid metabolism of neonatal piglets receiving TPN: effect of tyrosine precursors.. The American journal of physiology, 267 ((5 Pt 1)): (E672-E679). [PMID:7977717] |
24. P Labute,C Williams,M Feher,E Sourial,J M Schmidt. (2001-05-04) Flexible alignment of small molecules.. Journal of medicinal chemistry, 44 ((10)): (1483-1490). [PMID:11334559] |
25. L Ni,G J Tao,J Dai,Z Wang,S Y Xu. (2003-01-25) [Separation, purification and identification of angiotensin converting enzyme inhibitory silk fibroin peptide].. Se pu = Chinese journal of chromatography, 19 ((3)): (222-225). [PMID:12541801] |
26. Lidija Varga-Defterdarović,Gorana Hrlec. (2003-12-09) Synthesis and intramolecular reactions of Tyr-Gly and Tyr-Gly-Gly related 6-O-glucopyranose esters.. Carbohydrate research, 339 ((1)): (67-75). [PMID:14659672] |
27. Luqing Shang,Takehiko Maeda,Wenfang Xu,Shiroh Kishioka. (2008-03-18) Evaluation of a novel aminopeptidase N inhibitor, in vitro, using two assay systems.. Journal of enzyme inhibition and medicinal chemistry, 23 ((2)): (198-205). [PMID:18343904] |
28. Shanshan Wu,Chunchun Zhang,Ruyin Cao,Dingguo Xu,Hua Guo. (2011-07-08) pH-Dependent reactivity for glycyl-L-tyrosine in carboxypeptidase-A-catalyzed hydrolysis.. The journal of physical chemistry. B, 115 ((34)): (10360-10367). [PMID:21732684] |
29. Hiromichi Akizawa,Mitsuo Imajima,Hirofumi Hanaoka,Tomoya Uehara,Satoshi Satake,Yasushi Arano. (2013-01-22) Renal brush border enzyme-cleavable linkages for low renal radioactivity levels of radiolabeled antibody fragments.. Bioconjugate chemistry, 24 ((2)): (291-299). [PMID:23330714] |