GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC 50 of 38 nM for rGlyT1 Antipsychotic activity
In Vivo
GlyT1 Inhibitor 1 (Compound 46) demonstrates in vivo efficacy in a rat novel object recognition (NOR) assay after oral dosing at 0.1, 1, and 3 mg/kg . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:rGlyT1 38 nM (IC 50 )
Associated Targets
SLC6A9Tchem Sodium- and chloride-dependent glycine transporter 1 2 Activities
