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GNG2 Antibody - Primary antibody, specific to GNG2, Rabbit IgG

  • Carrier Free
  • ExactAb™
  • Validated
  • 0.5 mg/mL
Features and benefits
  • Short Overview:

    pAb; Rabbit anti Human GNG2 Antibody; WB, IHC; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse
  • Isotype: Rabbit IgG
    Application:
  • IHC
  • WB
Item Number
Ab105952
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab105952-10μl
10μl
In stock
$86.90
Ab105952-50μl
50μl
In stock
$259.90
Ab105952-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$379.90
Ab105952-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,999.90

pAb; Rabbit anti Human GNG2 Antibody; WB, IHC; Unconjugated

Basic Description

Product NameGNG2 Antibody - Primary antibody, specific to GNG2, Rabbit IgG
SynonymsG gamma I | GBG2_HUMAN | GNG 2 | Guanine nucleotide binding protein gamma 2 | G gamma I antibody | G gamma-I antibody | GBG2_HUMAN antibody | GNG 2 antibody | Gng2 antibody | Guanine nucleotide binding protein gamma 2 antibody | Guanine nucleotide-binding
Specifications & PurityExactAb™, Validated, Carrier Free, 0.5 mg/mL
Host speciesRabbit
SpecificityGNG2
ImmunogenA KLH conjugated synthetic peptide from of human GNG2 (AA 19-52)
Positive ControlWB: Human brain Lysates, Mouse brain Lysates. IHC: Human brain tissue.
ConjugationUnconjugated
GradeCarrier Free, ExactAb™, Validated
Product Description

Rabbit anti Human GNG2 Antibody, Polyclonal, could be used for WB, IHC and so on.
Application
WB: 1/1000
IHC: 1/100-1/500
Protein function
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodProtein A purified + Peptide Affinity purified
FormLiquid
Concentration0.5 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

GNG2 Antibody (Ab105952) - Western Blot
All lanes: GNG2 Antibody (Ab105952) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 8 kDa
Observed band size: 11 kDa
Exposure time: 33.1 s


GNG2 Antibody (Ab105952) - IHC
GNG2 Antibody (Ab105952) staining GNG2 in human brain tissue sections by Immunohistochemistry. Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH 6.0). Samples were incubated with GNG2 Antibody (Ab105952) (1/25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.

Associated Targets

GNG2 Tbio Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
IHC

1/100-1/500

WB

1/1000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0303298Certificate of AnalysisMar 15, 2024 Ab105952
ZJ24F0303297Certificate of AnalysisMar 15, 2024 Ab105952

Related Documents

References

1. Sharon Gauci,Andreas O Helbig,Monique Slijper,Jeroen Krijgsveld,Albert J R Heck,Shabaz Mohammed.  (2009-05-06)  Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach..  Analytical chemistry,  81  ((11)): (4493-4501).  [PMID:19413330]
2. Modarressi, M H MH, Taylor, K E KE and Wolfe, J J..  (2000)  Cloning, characterization, and mapping of the gene encoding the human G protein gamma 2 subunit..  Biochemical and biophysical research communications,    (7):   [PMID:10833460]
3. Bechtel, Stephanie S and 18 more authors..  (2007)  The full-ORF clone resource of the German cDNA Consortium..  BMC genomics,    (31):   [PMID:17974005]
4. Wang, Zhenglong Z and 9 more authors..  (2009)  Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5..  The Journal of biological chemistry,    (16):   [PMID:19713215]
5. Van Damme, Petra P and 15 more authors..  (2012)  N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB..  Proceedings of the National Academy of Sciences of the United States of America,    (31):   [PMID:22814378]
6. Stallmeyer, Birgit B and 12 more authors..  (2017)  A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction..  Circulation research,    (12):   [PMID:28219978]

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