GNG2 Antibody - Primary antibody, specific to GNG2, Rabbit IgG
Synonyms
G gamma I | GBG2_HUMAN | GNG 2 | Guanine nucleotide binding protein gamma 2 | G gamma I antibody | G gamma-I antibody | GBG2_HUMAN antibody | GNG 2 antibody | Gng2 antibody | Guanine nucleotide binding protein gamma 2 antibody | Guanine nucleotide-binding
Specifications & Purity
ExactAb™, Validated, Carrier Free, 0.5 mg/mL
Host species
Rabbit
Specificity
GNG2
Immunogen
A KLH conjugated synthetic peptide from of human GNG2 (AA 19-52)
Positive Control
WB: Human brain Lysates, Mouse brain Lysates. IHC: Human brain tissue.
Conjugation
Unconjugated
Grade
Carrier Free, ExactAb™, Validated
Product Description
Rabbit anti Human GNG2 Antibody, Polyclonal, could be used for WB, IHC and so on. Application WB: 1/1000 IHC: 1/100-1/500 Protein function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Product Properties
Isotype
Rabbit IgG
SDS-PAGE
150 kDa
Purification Method
Protein A purified + Peptide Affinity purified
Form
Liquid
Concentration
0.5 mg/mL
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Images
GNG2 Antibody (Ab105952) - Western Blot All lanes: GNG2 Antibody (Ab105952) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 8 kDa Observed band size: 11 kDa Exposure time: 33.1 s
GNG2 Antibody (Ab105952) - IHC GNG2 Antibody (Ab105952) staining GNG2 in human brain tissue sections by Immunohistochemistry. Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH 6.0). Samples were incubated with GNG2 Antibody (Ab105952) (1/25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.
Associated Targets
GNG2Tbio Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 0 Activities
1.Sharon Gauci,Andreas O Helbig,Monique Slijper,Jeroen Krijgsveld,Albert J R Heck,Shabaz Mohammed. (2009-05-06) Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.. Analytical chemistry, 81 ((11)):(4493-4501). [PMID:19413330]
2.Modarressi, M H MH, Taylor, K E KE and Wolfe, J J.. (2000) Cloning, characterization, and mapping of the gene encoding the human G protein gamma 2 subunit.. Biochemical and biophysical research communications, (7):[PMID:10833460]
3.Bechtel, Stephanie S and 18 more authors.. (2007) The full-ORF clone resource of the German cDNA Consortium.. BMC genomics, (31):[PMID:17974005]
4.Wang, Zhenglong Z and 9 more authors.. (2009) Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5.. The Journal of biological chemistry, (16):[PMID:19713215]
5.Van Damme, Petra P and 15 more authors.. (2012) N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.. Proceedings of the National Academy of Sciences of the United States of America, (31):[PMID:22814378]
6.Stallmeyer, Birgit B and 12 more authors.. (2017) A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction.. Circulation research, (12):[PMID:28219978]
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