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GOAT-IN-1 - 99%, high purity , CAS No.1452473-54-9

  • ≥99%
Item Number
G646272
Grouped product items
SKUSizeAvailabilityPrice Qty
G646272-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$511.90
G646272-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$796.90

Basic Description

Specifications & Purity≥99%
Biochemical and Physiological MechanismsGOAT-IN-1 is an inhibitor of ghrelin O-acyltransferase (GOAT) , which could be useful for the prophylaxis or treatment of obesity, diabetes, hyperlipidemia, metabolic, non-alcoholic fatty liver, steatohepatitis, sarcopenia, appetite control, alcohol/narco
Storage TempStore at 2-8°C,Desiccated
Shipped InWet ice
Product Description

GOAT-IN-1 is an inhibitor of ghrelin O-acyltransferase (GOAT) , which could be useful for the prophylaxis or treatment of obesity, diabetes, hyperlipidemia, metabolic, non-alcoholic fatty liver, steatohepatitis, sarcopenia, appetite control, alcohol/narcotic dependence, Alzheimer’s disease, Parkinson’s disease, cerebrovascular dementia, cerebral apoplexy, cerebral infarction, cardic disease, some kind of tumors.

In Vitro

The inhibitory activity of GOAT-IN-1 (Example 16) for human GOAT is 101% with the concentration of 10 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Associated Targets

MBOAT4 Tchem Ghrelin O-acyltransferase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 2-[4-chloro-6-[[2-methyl-6-(trifluoromethyl)pyridin-3-yl]methoxy]-1-benzothiophen-3-yl]acetic acid
INCHI InChI=1S/C18H13ClF3NO3S/c1-9-10(2-3-15(23-9)18(20,21)22)7-26-12-5-13(19)17-11(4-16(24)25)8-27-14(17)6-12/h2-3,5-6,8H,4,7H2,1H3,(H,24,25)
InChi Key IXAAPJMGWLXOIL-UHFFFAOYSA-N
Canonical SMILES CC1=C(C=CC(=N1)C(F)(F)F)COC2=CC3=C(C(=C2)Cl)C(=CS3)CC(=O)O
Isomeric SMILES CC1=C(C=CC(=N1)C(F)(F)F)COC2=CC3=C(C(=C2)Cl)C(=CS3)CC(=O)O
PubChem CID 89767718
Molecular Weight 415.81

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 150 mg/mL (360.74 mM; ultrasonic and warming and heat to 60°C)

Related Documents

Solution Calculators