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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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G646272-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $511.90 | |
G646272-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $796.90 |
Specifications & Purity | ≥99% |
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Biochemical and Physiological Mechanisms | GOAT-IN-1 is an inhibitor of ghrelin O-acyltransferase (GOAT) , which could be useful for the prophylaxis or treatment of obesity, diabetes, hyperlipidemia, metabolic, non-alcoholic fatty liver, steatohepatitis, sarcopenia, appetite control, alcohol/narco |
Storage Temp | Store at 2-8°C,Desiccated |
Shipped In | Wet ice |
Product Description | GOAT-IN-1 is an inhibitor of ghrelin O-acyltransferase (GOAT) , which could be useful for the prophylaxis or treatment of obesity, diabetes, hyperlipidemia, metabolic, non-alcoholic fatty liver, steatohepatitis, sarcopenia, appetite control, alcohol/narcotic dependence, Alzheimer’s disease, Parkinson’s disease, cerebrovascular dementia, cerebral apoplexy, cerebral infarction, cardic disease, some kind of tumors. In Vitro The inhibitory activity of GOAT-IN-1 (Example 16) for human GOAT is 101% with the concentration of 10 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | 2-[4-chloro-6-[[2-methyl-6-(trifluoromethyl)pyridin-3-yl]methoxy]-1-benzothiophen-3-yl]acetic acid |
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INCHI | InChI=1S/C18H13ClF3NO3S/c1-9-10(2-3-15(23-9)18(20,21)22)7-26-12-5-13(19)17-11(4-16(24)25)8-27-14(17)6-12/h2-3,5-6,8H,4,7H2,1H3,(H,24,25) |
InChi Key | IXAAPJMGWLXOIL-UHFFFAOYSA-N |
Canonical SMILES | CC1=C(C=CC(=N1)C(F)(F)F)COC2=CC3=C(C(=C2)Cl)C(=CS3)CC(=O)O |
Isomeric SMILES | CC1=C(C=CC(=N1)C(F)(F)F)COC2=CC3=C(C(=C2)Cl)C(=CS3)CC(=O)O |
PubChem CID | 89767718 |
Molecular Weight | 415.81 |
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Solubility | DMSO : 150 mg/mL (360.74 mM; ultrasonic and warming and heat to 60°C) |
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