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Gomisin J - 99%, high purity , CAS No.66280-25-9

  • ≥99%
Item Number
G647095
Grouped product items
SKUSizeAvailabilityPrice Qty
G647095-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$50.90
G647095-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$150.90
G647095-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$250.90

Phenylpropanoids Lignans Phenols Monophenols

Basic Description

SynonymsGomisin J|66280-25-9|(-)-Gomisin J|UNII-X13A57600T|X13A57600T|DTXSID30216490|(9S,10R)-3,4,15,16-tetramethoxy-9,10-dimethyltricyclo[10.4.0.02,7]hexadeca-1(16),2,4,6,12,14-hexaene-5,14-diol|Gomisin-J|DIBENZO(A,C)CYCLOOCTENE-3,10-DIOL, 5,6,7,8-TETRAHYDRO-1,2
Specifications & Purity≥99%
Biochemical and Physiological MechanismsGomisin J is a small molecular weight lignan found in Schisandra chinensis and has been demonstrated to have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammato
Storage TempProtected from light,Store at -80°C
Shipped InIce chest + Ice pads
Product Description

Gomisin J is a small molecular weight lignan found in Schisandra chinensis and has been demonstrated to have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK , LKB1 and Ca 2+ /calmodulin-dependent protein kinase II and inhibition of fetuin-A in HepG2 cells. gomisin J has potential benefits in treating nonalcoholic fatty liver disease .

Form:Solid

Associated Targets

PTGS2 Tclin Prostaglandin G/H synthase 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (9R,10S)-3,4,15,16-tetramethoxy-9,10-dimethyltricyclo[10.4.0.02,7]hexadeca-1(16),2,4,6,12,14-hexaene-5,14-diol
INCHI InChI=1S/C22H28O6/c1-11-7-13-9-15(23)19(25-3)21(27-5)17(13)18-14(8-12(11)2)10-16(24)20(26-4)22(18)28-6/h9-12,23-24H,7-8H2,1-6H3/t11-,12+
InChi Key PICOUNAPKDEPCA-TXEJJXNPSA-N
Canonical SMILES CC1CC2=CC(=C(C(=C2C3=C(C(=C(C=C3CC1C)O)OC)OC)OC)OC)O
Isomeric SMILES C[C@@H]1CC2=CC(=C(C(=C2C3=C(C(=C(C=C3C[C@@H]1C)O)OC)OC)OC)OC)O
PubChem CID 3001686
Molecular Weight 388.45

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 100 mg/mL (257.43 mM; Need ultrasonic)

Related Documents

Solution Calculators