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- Granisetron hydrochloride - 98%, high purity , Serotonin 3a (5-HT3a) receptor antagonist, CAS No.107007-99-8, Serotonin 3a (5-HT3a) receptor antagonist
Granisetron hydrochloride - 98%, high purity , Serotonin 3a (5-HT3a) receptor antagonist, CAS No.107007-99-8, Serotonin 3a (5-HT3a) receptor antagonist
Basic Description
Synonyms | Granisetron hydrochloride|Granisetron HCl|107007-99-8|Granisetron (Hydrochloride)|NSC-759839|1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)indazole-3-carboxamide;hydrochloride|1-METHYL-1H-INDAZOLE-3-CARBOXYLIC ACID (9-METHYL-9-AZA-BICYCLO[3.3.1]NON-3 |
Specifications & Purity | 98% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Action Type | ANTAGONIST |
Mechanism of action | Serotonin 3a (5-HT3a) receptor antagonist |
Product Description | Granisetron (BRL 43694) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.
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Names and Identifiers
IUPAC Name | 1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)indazole-3-carboxamide;hydrochloride |
INCHI | InChI=1S/C18H24N4O.ClH/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17;/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23);1H |
InChi Key | QYZRTBKYBJRGJB-UHFFFAOYSA-N |
Canonical SMILES | CN1C2CCCC1CC(C2)NC(=O)C3=NN(C4=CC=CC=C43)C.Cl |
Isomeric SMILES | CN1C2CCCC1CC(C2)NC(=O)C3=NN(C4=CC=CC=C43)C.Cl |
WGK Germany | 3 |
RTECS | NK7882200 |
PubChem CID | 65264 |
Molecular Weight | 348.87 |
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Chemical and Physical Properties
Melt Point(°C) | 284.0-290.0°C |
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Safety and Hazards(GHS)
Pictogram(s) | GHS07 |
Signal | Warning |
Hazard Statements | H302:Harmful if swallowed |
Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
WGK Germany | 3 |
RTECS | NK7882200 |
Merck Index | 4536 |
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