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Home Epigenetics GSK-LSD1 Dihydrochloride - ≥98%, high purity , CAS No.2102933-95-7
GSK-LSD1 Dihydrochloride - ≥98%, high purity , CAS No.2102933-95-7
Potent and selective LSD1 inhibitor
Basic Description Specifications & Purity ≥98% Biochemical and Physiological Mechanisms Potent and selective lysine specific demethylase 1 (LSD1) inhibitor (IC50= 16 nM). Exhibits >1000-fold selectivity for LSD1 over closely related enzymes including LSD2, MAO-1 and MAO-B. Inhibits cancer cell line growthin vitro. Storage Temp Store at 2-8°C Shipped In Wet ice
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name N-[(1R,2S)-2-phenylcyclopropyl]piperidin-4-amine;dihydrochloride INCHI InChI=1S/C14H20N2.2ClH/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12;;/h1-5,12-16H,6-10H2;2*1H/t13-,14+;;/m0../s1 InChi Key PJFZOGMSPBHPNS-WICJZZOFSA-N Canonical SMILES C1CNCCC1NC2CC2C3=CC=CC=C3.Cl.Cl Isomeric SMILES C1CNCCC1N[C@@H]2C[C@H]2C3=CC=CC=C3.Cl.Cl PubChem CID 91663353 Molecular Weight 289.24
Chemical and Physical Properties Solubility Solvent:water, Max Conc. mg/mL: 28.92, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 28.92, Max Conc. mM: 100
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