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GSK3527497 - ≥98%, high purity , CAS No.2215855-22-2, Inhibitor of TRPV6

  • Moligand™
  • ≥98%
Item Number
G610717
Grouped product items
SKUSizeAvailabilityPrice Qty
G610717-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
G610717-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$879.90
G610717-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,232.90
G610717-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,156.90

Basic Description

Synonymscompound 13;GSK-3527497
Specifications & Purity≥98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of TRPV6
Product Description

GSK3527497 is a novel potent and selective inhibitor of transient receptor potential vanilloid-4 (TRPV4).

Associated Targets

TRPV6 Tchem Transient receptor potential cation channel subfamily V member 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TRPV4 Tchem Transient receptor potential cation channel subfamily V member 4 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Molecular Weight 426.85

Certificates

Certificate of Analysis(COA)

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Related Documents

References

1. Brooks CA, Barton LS, Behm DJ, Brnardic EJ, Costell MH, Holt DA, Jolivette LJ, Matthews JM, McAtee JJ, McCleland BW et al..  (2019)  Discovery of GSK3527497: A Candidate for the Inhibition of Transient Receptor Potential Vanilloid-4 (TRPV4)..  J Med Chem,  62  (20): (9270-9280).  [PMID:31532662]

Solution Calculators