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GTP-γ-S-Li4 - ≥90%, high purity , CAS No.94825-44-2
Discover GTP-γ-S-Li4 by Aladdin Scientific in ≥90% for only $61.90. Available - in Ligands at Aladdin Scientific. G-protein-activating GTP analog Tags: .
Basic Description Synonyms 94825-44-2|EINECS 305-606-1|Guanosine 5'-[gamma-thio]triphosphate tetralithium salt|Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid, tetralithium salt|CHEMBL1627119|tetralithium;[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-y Specifications & Purity ≥90% Storage Temp Store at -20°C,Desiccated Shipped In Dry ice Product Description Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Names and Identifiers Pubchem Sid 488202914 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488202914 IUPAC Name tetralithium;[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] dioxidophosphinothioyl phosphate INCHI InChI=1S/C10H16N5O13P3S.4Li/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(26-9)1-25-29(19,20)27-30(21,22)28-31(23,24)32;;;;/h2-3,5-6,9,16-17H,1H2,(H,19,20)(H,21,22)(H2,23,24,32)(H3,11,13,14,18);;;;/q;4*+1/p-4/t3-,5-,6-,9-;;;;/m1..../s1 InChi Key AMQXJFWJOAWCPV-ZVQJTLEUSA-J Canonical SMILES [Li+].[Li+].[Li+].[Li+].C1=NC2=C(N1C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=S)([O-])[O-])O)O)N=C(NC2=O)N Isomeric SMILES [Li+].[Li+].[Li+].[Li+].C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)([O-])OP(=S)([O-])[O-])O)O)N=C(NC2=O)N WGK Germany 3 PubChem CID 135445735 Molecular Weight 567
Chemical and Physical Properties Solubility Soluble in water to 100 mM
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
WGK Germany 3 RIDADR NONHforallmodesoftransport
References 1. Kutsch M et al.. (2020) Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions.. EMBO J, 39 (13): (e104926). [PMID:32510692 ] 2. Wandel MP et al.. (2020) Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms.. Nat Immunol, 21 (8): (880-891). [PMID:32541830 ] 3. Kovalski JR et al.. (2019) The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.. Mol Cell, 73 (4): (830-844.e12). [PMID:30639242 ]
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