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Guanabenz Acetate - >98.0%(HPLC), high purity , Adrenergic receptor alpha-2 agonist, CAS No.23256-50-0, Adrenergic receptor alpha-2 agonist

≥98%(HPLC)

CAS#: 23256-50-0
Formula: C₈H₈Cl₂N₄·C₂H₄O₂
Molecular Weight: 291.13
MDL number: MFCD00153801
PubChem CID: 5702062

Item Number

G156852

Grouped product items
SKU	Size	Availability	Price
G156852-200mg	200mg	In stock	$29.90
G156852-1g	1g	In stock	$92.90
G156852-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$325.90

Centrally acting, selective alpha 2 adrenoceptor agonist

View related series

Guanidines

Basic Description

Synonyms	Guanabenz acetate\|23256-50-0\|Wytensin\|WY-8678 acetate\|Guanabenz (Acetate)\|Guanabenz monoacetate\|Guanabenz acetate salt\|WY 8678 acetate\|UNII-443O19GK1A\|HSDB 6535\|443O19GK1A\|EINECS 245-534-7\|NSC-757044\|MLS000028717\|60329-04-6\|Guanabenz (WY-8678) Acetate\|((2
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Centrally acting, selective alpha 2 adrenoceptor agonist. I 2 imidazoline binding site selective ligand. Antihypertensive.
Shipped In	Normal
Action Type	AGONIST
Mechanism of action	Adrenergic receptor alpha-2 agonist
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Guanabenz Acetate is a specific agonist of Adrenergic Receptor. The pEC50 for α2a-Adrenergic Receptor, α2b-Adrenergic Receptor and α2c-Adrenergic Receptor is 8.25, 7.01 and ~5, respectively.

Associated Targets

GMNN Tbio Geminin 0 Activities

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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

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SNCA Tchem Alpha-synuclein 0 Activities

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LMNA Tbio Prelamin-A/C 0 Activities

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BLM Tchem Bloom syndrome protein 0 Activities

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

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KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

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IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

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NPSR1 Tchem Neuropeptide S receptor 0 Activities

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Names and Identifiers

IUPAC Name	acetic acid;2-[(E)-(2,6-dichlorophenyl)methylideneamino]guanidine
INCHI	InChI=1S/C8H8Cl2N4.C2H4O2/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12;1-2(3)4/h1-4H,(H4,11,12,14);1H3,(H,3,4)/b13-4+;
InChi Key	MCSPBPXATWBACD-GAYQJXMFSA-N
Canonical SMILES	CC(=O)O.C1=CC(=C(C(=C1)Cl)C=NN=C(N)N)Cl
Isomeric SMILES	CC(=O)O.C1=CC(=C(C(=C1)Cl)/C=N/N=C(N)N)Cl
WGK Germany	3
RTECS	MF0382000
PubChem CID	5702062
Molecular Weight	291.13

Certificates

Certificate of Analysis(COA)

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12 results found

Lot Number	Certificate Type	Date	Item
D2416305	Certificate of Analysis	Apr 07, 2024	G156852
D2416322	Certificate of Analysis	Apr 07, 2024	G156852
D2416323	Certificate of Analysis	Apr 07, 2024	G156852
D2411076	Certificate of Analysis	Nov 21, 2023	G156852
L2301174	Certificate of Analysis	Nov 21, 2023	G156852
L2301308	Certificate of Analysis	Nov 21, 2023	G156852
L2301309	Certificate of Analysis	Nov 21, 2023	G156852
L2301310	Certificate of Analysis	Nov 21, 2023	G156852
J1916218	Certificate of Analysis	Aug 04, 2023	G156852
J2317013	Certificate of Analysis	Aug 04, 2023	G156852
G2319082	Certificate of Analysis	Jul 28, 2023	G156852
G2319083	Certificate of Analysis	Jul 24, 2023	G156852

Solubility

Slightly soluble in water; Degree of Solubility in water: 11 g/l 25 °C; Soluble in Alcohol; Very slightly soluble in Chloroform

Sensitivity

Light sensitive

Melt Point(°C)

188-192℃

Safety and Hazards(GHS)

Pictogram(s)	GHS06
Signal	Danger
Hazard Statements	H301:Toxic if swallowed
Precautionary Statements	P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately.
WGK Germany	3
RTECS	MF0382000
Merck Index	4558

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