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Guanidine hydrochloride - ≥99% (titration), organic base and chaeotropic agent, high purity , CAS No.50-01-1

≥99%(T)
organic base and chaeotropic agent

CAS#: 50-01-1
Formula: NH₂C(=NH)NH₂ · HCl
Molecular Weight: 95.53
Beilstein Registry Number: 3591990
EC Number: 200-002-3
PubChem CID: 5742

Item Number

G432765

Grouped product items
SKU	Size	Availability	Price
G432765-25g	25g	In stock	$99.90
G432765-100g	100g	In stock	$295.90
G432765-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$831.90

Basic Description

Synonyms	Guanidine hydrochloride\|50-01-1\|Guanidinium chloride\|guanidine HCl\|Aminoformamidine hydrochloride\|Guanidine, monohydrochloride\|Aminomethanamidine hydrochloride\|Guanidine (hydrochloride)\|Guanidinehydrochloride\|GUANIDINE MONOHYDROCHLORIDE\|Iminourea hydrochl
Specifications & Purity	≥99%(T), organic base and chaeotropic agent
Biochemical and Physiological Mechanisms	Guanidine hydrochloride (GdnHCl) is hydroscopic and a small molecule. It is a potent denaturant of enzymes, which results in conformational changes in the enzyme, leading to complete loss of enzyme activity. GdnHCl is involved in blocking the activity of
Note	注意: 在储存过程中可能会结块。产品的质量似乎并没有受到影响，而且由自由流动和块状的盐酸胍制备的溶液似乎是一样的。对于松散材料，请查看我们的Redi-Dri ™ 松散产品货号RDD001。
Product Description	Gene Information human ... KCNA1(3736), KCNA10(3744), KCNA2(3737), KCNA3(3738), KCNA4(3739), KCNA5(3741), KCNA6(3742), KCNA7(3743), KCNB1(3745), KCNB2(9312), KCNC1(3746), KCNC2(3747), KCNC3(3748), KCNC4(3749), KCND1(3750), KCND2(3751), KCND3(3752), KCNF1(3754), KCNG1(3755 Application Guanidine hydrochloride (GdnHCl) has been used: to perform absolute quantitation of amyloid-beta (Aß) isoforms in plasma in protein carbonylation assay for the quantification of glycosaminoglycans (GAG) for denaturation of cow′s milk allergens as a control in antiviral screening tests with coxsackievirus B3 (CVB3) in RNA isolation to dissociate nucleoproteins and inhibit RNase Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

Associated Targets

LDHB Tchem L-lactate dehydrogenase B chain 0 Activities

Discover Target: LDHB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

C5 Tclin Complement C5 0 Activities

Discover Target: C5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	guanidine;hydrochloride
INCHI	InChI=1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H
InChi Key	PJJJBBJSCAKJQF-UHFFFAOYSA-N
Canonical SMILES	C(=N)(N)N.Cl
Isomeric SMILES	C(=N)(N)N.Cl
WGK Germany	1
RTECS	MF4300000
PubChem CID	5742
Molecular Weight	95.53
Beilstein	3591990

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

6 results found

Lot Number	Certificate Type	Date	Item
E23301352	Certificate of Analysis	Jun 08, 2023	G432765
E23301272	Certificate of Analysis	Jun 08, 2023	G432765
E23301274	Certificate of Analysis	Jun 08, 2023	G432765
E23301340	Certificate of Analysis	Jun 08, 2023	G432765
G2319562	Certificate of Analysis	Jun 08, 2023	G432765
G2319575	Certificate of Analysis	Jun 08, 2023	G432765

Chemical and Physical Properties

Solubility	H2O: 6M
Melt Point(°C)	178-185°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H302:Harmful if swallowed
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help.
WGK Germany	1
RTECS	MF4300000
Merck Index	4562

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