GW284543 - 99%, high purity , CAS No.790186-68-4

Item Number

G647296

Grouped product items
SKU	Size	Availability	Price
G647296-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$90.90
G647296-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$140.90
G647296-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$450.90
G647296-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$750.90

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Basic Description

Specifications & Purity	99%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	GW284543 (UNC10225170) is a selective MEK5 inhibitor. GW284543 reduces pERK5, and decreases endogenous MYC protein In Vitro GW284543 (10 and 20 μM; 6 h) treatment inhibits MEK5 in a dose-dependent manner and reduces pERK5. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot AnalysisCell Line: MIA PaCa-2 cells Concentration: 10 and 20 μM Incubation Time: 6 hours Result: Reduced phosphorylation of ERK5, and decreased endogenous MYC protein. Form:Solid IC50& Target:MEK5

Names and Identifiers

IUPAC Name	6,7-dimethoxy-N-(3-phenoxyphenyl)quinolin-4-amine
INCHI	InChI=1S/C23H20N2O3/c1-26-22-14-19-20(11-12-24-21(19)15-23(22)27-2)25-16-7-6-10-18(13-16)28-17-8-4-3-5-9-17/h3-15H,1-2H3,(H,24,25)
InChi Key	LEEMRFWMAIVHQY-UHFFFAOYSA-N
Canonical SMILES	COC1=CC2=C(C=CN=C2C=C1OC)NC3=CC(=CC=C3)OC4=CC=CC=C4
Isomeric SMILES	COC1=CC2=C(C=CN=C2C=C1OC)NC3=CC(=CC=C3)OC4=CC=CC=C4
PubChem CID	44531022
Molecular Weight	372.4

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Basic Description