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GW441756 hydrochloride , CAS No.504433-24-3(free base)
a highly selective TrkA kinase inhibitor
Basic Description
Synonyms | 504433-24-3 (free base) | 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one hydrochloride | (3Z)-3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one; hydrochloride. | GW441756 hydrochloride, >=97% (HPLC), powd |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Product Description | A highly selective, potent TrkA kinase inhibitor which is orally active. IC|50|= 2 nM. |
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Names and Identifiers
Canonical SMILES | CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC=N4)NC3=O.Cl |
Isomeric SMILES | CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC=N4)NC3=O.Cl |
PubChem CID | 16219400 |
Molecular Weight | 311.77 |
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Chemical and Physical Properties
Solubility | Soluble in Water: 10 mg/mL |
Melt Point(°C) | ≥ 270° C |
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