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GW841819X - 98%, high purity , CAS No.146135-18-4, Inhibitor of bromodomain containing 2;Inhibitor of bromodomain containing 3;Inhibitor of bromodomain containing 4

Moligand™
≥98%

CAS#: 146135-18-4
Formula: C₂₅H₂₁N₅O₂
Molecular Weight: 423.47
PubChem CID: 13953710

Item Number

G610775

Grouped product items
SKU	Size	Availability	Price	Qty
G610775-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$922.90
G610775-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$899.90

View related series

bromodomain containing 2 Inhibitor bromodomain containing 3 Inhibitor bromodomain containing 4 Inhibitor

Basic Description

Synonyms	KB-75882
Specifications & Purity	Moligand™, ≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of bromodomain containing 2;Inhibitor of bromodomain containing 3;Inhibitor of bromodomain containing 4
Product Description	GW841819X is an analogue of (+)-JQ1 and a novel inhibitor of BET bromodomains.

Associated Targets

CREBBP Tchem CREB-binding protein 0 Activities

Discover Target: CREBBP

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

BRD4 Tchem Bromodomain-containing protein 4 6 Activities

Discover Target: BRD4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

BRD3 Tchem Bromodomain-containing protein 3 4 Activities

Discover Target: BRD3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

BRD2 Tchem Bromodomain-containing protein 2 8 Activities

Discover Target: BRD2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ATAD2 Tchem ATPase family AAA domain-containing protein 2 0 Activities

Discover Target: ATAD2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	benzyl N-(1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl)carbamate
INCHI	InChI=1S/C25H21N5O2/c1-17-28-29-24-23(27-25(31)32-16-18-10-4-2-5-11-18)26-22(19-12-6-3-7-13-19)20-14-8-9-15-21(20)30(17)24/h2-15,23H,16H2,1H3,(H,27,31)
InChi Key	TUWDLUFFAHHNEF-UHFFFAOYSA-N
Canonical SMILES	CC1=NN=C2N1C3=CC=CC=C3C(=NC2NC(=O)OCC4=CC=CC=C4)C5=CC=CC=C5
Isomeric SMILES	CC1=NN=C2N1C3=CC=CC=C3C(=NC2NC(=O)OCC4=CC=CC=C4)C5=CC=CC=C5
PubChem CID	13953710
Molecular Weight	423.47

ChEMBL Ligand

CHEMBL2153434

PubChem CID

13953710

CAS Registry No.

146135-18-4

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