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GYKI53655 , CAS No.143692-18-6, Antagonist of GluA1;Antagonist of GluA2;Antagonist of GluA3;Antagonist of GluA4

Moligand™

CAS#: 143692-18-6
PubChem CID: 126758

Item Number

G610778

Grouped product items
SKU	Size	Availability	Price	Qty
G610778-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$572.90
G610778-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

GluA1 Antagonist GluA2 Antagonist GluA3 Antagonist GluA4 Antagonist

Basic Description

Synonyms	143692-18-6\|1-(4-AMINOPHENYL)-3-METHYLCARBAMOYL-4-METHYL-7,8-METHYLENEDIOXY-3,4-DIHYDRO-5H-2,3-BENZODIAZEPINE\|GYKI-53655\|Gyki 53655\|GYKI53655\|GYKI-53655 free base\|LY-300168\|X46FC5N190\|UNII-X46FC5N190\|CHEMBL267450\|LY-300168, (+/-)-\|5-(4-aminophenyl)-N,8-di
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of GluA1;Antagonist of GluA2;Antagonist of GluA3;Antagonist of GluA4

Associated Targets

YES1 Tclin Tyrosine-protein kinase Yes 0 Activities

Discover Target: YES1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIA4 Tclin Glutamate receptor 4 0 Activities

Discover Target: GRIA4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIA2 Tclin Glutamate receptor 2 0 Activities

Discover Target: GRIA2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIA3 Tclin Glutamate receptor 3 0 Activities

Discover Target: GRIA3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIA1 Tclin Glutamate receptor 1 0 Activities

Discover Target: GRIA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide
INCHI	InChI=1S/C19H20N4O3/c1-11-7-13-8-16-17(26-10-25-16)9-15(13)18(22-23(11)19(24)21-2)12-3-5-14(20)6-4-12/h3-6,8-9,11H,7,10,20H2,1-2H3,(H,21,24)
InChi Key	SMGACXZFVXKEAX-UHFFFAOYSA-N
Canonical SMILES	CC1CC2=CC3=C(C=C2C(=NN1C(=O)NC)C4=CC=C(C=C4)N)OCO3
Isomeric SMILES	CC1CC2=CC3=C(C=C2C(=NN1C(=O)NC)C4=CC=C(C=C4)N)OCO3
Alternate CAS	143692-18-6
PubChem CID	126758
MeSH Entry Terms	1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine;GYKI 53655;GYKI-53655;LY 300168

CAS Registry No.

143692-18-6

PubChem CID

126758

ChEMBL Ligand

CHEMBL267450

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