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H-Ile-Pro-Pro-OH hydrochloride - 10mM in DMSO, high purity , CAS No.1208862-61-6(DMSO)

  • 10mM in DMSO
Item Number
H655558
Grouped product items
SKUSizeAvailabilityPrice Qty
H655558-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$88.90

Basic Description

Specifications & Purity10mM in DMSO
Storage TempProtected from light,Desiccated,Store at -80°C
Shipped InIce chest + Ice pads
Product Description

H-Ile-Pro-Pro-OH hydrochloride, a milk-derived peptide , inhibits angiotensin-converting enzyme ( ACE ) with an IC 50 of 5 μM . Antihypertensive tripeptides

In Vitro

Ile-Pro-Pro (IPP; 1 nM, 0.1 μM, and 10 μM) increases nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Ile-Pro-Pro (IPP; 30 mg/kg per day; 0.3 g/L) attenuates arterial dysfunction in L-NAME-treated rats Ile-Pro-Pro decreases blood pressure in spontaneously hypertensive rats (SHR) . Ile-Pro-Pro attenuates the development of atherosclerosis in apolipoprotein E-deficient (apoE(-/-)) mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:IC50: 5 μM (ACE)

Names and Identifiers

Canonical SMILES CCC(C)C(C(=O)N1CCCC1C(=O)N2CCCC2C(=O)O)N.Cl
Molecular Weight 361.86

Certificates

Certificate of Analysis(COA)

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Related Documents

Solution Calculators