H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC 50 of 19 nM.
In Vitro
H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC 50 of 19 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
H4 Receptor antagonist 1 indicates that metabolic stability in rat microsomes is very low with only 1% parent compound remaining after 10 min incubation . MCE has not independently confirmed the accuracy of these methods. They are for reference only.