H8 dihydrochloride - ≥98%, high purity , CAS No.113276-94-1

Item Number

H276181

• Synonyms: H-8 dihydrochloride|113276-94-1|H-8, Dihydrochloride|N-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamide dihydrochloride|H-8 (dihydrochloride)|H8 dihydrochloride|H-8 (hydrochloride)|N-(2-(Methylamino)ethyl)isoquinoline-5-sulfonamide dihydrochloride|H8|N-(2
• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: cGMP- and cAMP-dependent kinases inhibitor. Inhibits the activity of PKG (K i = 0.48 µM) and PKA (K i = 1.2 µM). Also inhibits PKC (K i = 15 µM) and myosin-light chain kinase (MLCK; K i = 68 µM) activity.
• Storage Temp: Store at -20°C,Desiccated
• Shipped In: Ice chest + Ice pads
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

H-8 (dihydrochloride) is a cell-permeable, reversible and ATP-competitive PKA inhibitor.