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Harzianum A - ≥95%, high purity , CAS No.156250-74-7
an anticancer compound that is cytotoxic to human cancer cell lines
Basic Description Synonyms Harzianum A|156250-74-7|(2E,4E,6E)-8-Oxo-8-(1,2,5-trimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-11-yl)oxyocta-2,4,6-trienoic acid|Harzianum B|CID 6444304|Trichothec-9-en-4-ol|HB3926|Trichodermyl 2',4',6'-octatriendioate|J-009289|Trich Specifications & Purity ≥95% Source Trichodermasp. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description Harzianum A is an anticancer compound that is cytotoxic to human cancer cell lines.
Harzianum A, a trichothecene isolated from the soil-borne fungus Trichoderma harzianum, exhibits no cytotoxicity against baby hamster kidney cells and lacks activity against both Gram-negative and Gram-positive bacteria. However, it demonstrates modest antifungal activity at a concentration of 100 μg/mL .
Names and Identifiers IUPAC Name (2E,4E,6E)-8-oxo-8-(1,2,5-trimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-11-yl)oxyocta-2,4,6-trienoic acid INCHI InChI=1S/C23H28O6/c1-15-10-11-21(2)16(12-15)28-18-13-17(22(21,3)23(18)14-27-23)29-20(26)9-7-5-4-6-8-19(24)25/h4-9,12,16-18H,10-11,13-14H2,1-3H3,(H,24,25)/b5-4+,8-6+,9-7+ InChi Key FVRDNLIUSWSBCT-WUJFNTSISA-N Canonical SMILES CC1=CC2C(CC1)(C3(C(CC(C34CO4)O2)OC(=O)C=CC=CC=CC(=O)O)C)C Isomeric SMILES CC1=CC2C(CC1)(C3(C(CC(C34CO4)O2)OC(=O)/C=C/C=C/C=C/C(=O)O)C)C PubChem CID 6444304 Molecular Weight 400.47
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