HDAC-IN-4 - 10mM in DMSO, high purity , CAS No.1252003-13-6(DMSO)

  • 10mM in DMSO
Item Number
H655876
Grouped product items
SKUSizeAvailabilityPrice Qty
H655876-1ml
1ml
Available within 8-12 weeks(?)
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$165.90

Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor with pIC 50 s of 7.2 and 6.8 in BRET assay, respectively. Antitumoral activity

In Vitro

HDAC-IN-4 inhibits HDAC1, HDAC2, HDAC3, HDAC8 and HDAC10 with pIC 50 s of 5.5, 4.6, 5.4, 5.4, 6.7 in FRET assay, respectively. HDAC-IN-4 is more potent against HDAC6 than Tubastatin A, suggests that HDAC-IN-4 may be a better HDAC6 probe than Tubastatin A. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:pIC50: 7.2 (HDAC6), and 6.8 (HDAC10)

Names and Identifiers

Canonical SMILES CN1CCC2=C(C1)N(C3=CC=CC=C23)CC4=CC=C(C=C4)C(=O)NO.Cl
Molecular Weight 371.87

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