Hemopexin is a single-chain protein belonging to the family of blood transport proteins. It binds to heme released into the bloodstream during the degradation process. Recent studies have demonstrated that hemopexin acts as an extracellular antioxidant against hemoglobin-mediated damage in inflammation. Hemopexin protects against heme toxicity and conserves and recycles iron. Abnormal levels of hemopexin are associated with hemolytic anemia, chronic neuromuscular disease, and acute intermittent porphyria.
Prepared from Rat Serum in the Athens Research & Technology laboratory.
Country of Origin: Rat serum was obtained from healthy animals of US origin and under the care of a registered veterinarian.
Product Citation: Vercellotti GM, Zhang P, Nguyen J, Abdulla F, et al. Hepatic Overexpression of Hemopexin Inhibits Inflammation and Vascular Stasis in Murine Models of Sickle Cell Disease. Mol Med. 2016 Jul 19;22. doi: 10.2119/molmed.2016.00063. [Epub ahead of print]
Specifications & Purity
≥95%(SDS-PAGE)
Product Specifications
Form
Lyophilized from 11.9 mM phosphate, 137 mM NaCl, 2.7 mM KCl, pH 7.4.
