HENECA - ≥99%, high purity , CAS No.141018-30-6, Agonist of A 1 receptor;Agonist of A 2A receptor;Agonist of A 2B receptor;Agonist of A 3 receptor

Item Number

H275298

• Synonyms: 2-Hexynyl-NECA|HE-NECA|141018-30-6|Heneca|2-Hexynyl-5'-N-ethylcarboxamidoadenosine|(2S,3S,4R,5R)-5-(6-amino-2-hex-1-ynylpurin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide|CHEMBL410873|beta-D-Ribofuranuronamide, 1-[6-amino-2-(1-hexyn-1-yl)-9H-purin-9-y
• Specifications & Purity: Moligand™, ≥99%
• Biochemical and Physiological Mechanisms: Selective A 2A receptor agonist (K i = 2.2 nM). Shows good selectivity for A 2A over A 1 receptors. Displays antiaggregatory activity. Increases cAMP accumulation (EC 50 = 43 nM) and inhibits superoxide anion production (EC 50 = 3.63 nM) in neutrophils.
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: AGONIST
• Mechanism of action: Agonist of A 1 receptor;Agonist of A 2A receptor;Agonist of A 2B receptor;Agonist of A 3 receptor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Store at +4°C. The product can be stored for up to 12 months.