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Herkinorin - ≥98%, high purity , CAS No.862073-77-6

≥98%

CAS#: 862073-77-6
Formula: C₂₈H₃₀O₈
Molecular Weight: 494.53
PubChem CID: 11431898

Item Number

H274914

Grouped product items
SKU	Size	Availability	Price	Qty
H274914-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$137.90

Discover Herkinorin by Aladdin Scientific in ≥98% for only $137.90. Available - in Ligands at Aladdin Scientific. Non-internalising μ opioid agonist Tags: .

Basic Description

Synonyms	herkinorin\|862073-77-6\|5XN29VGR24\|UNII-5XN29VGR24\|CHEMBL363324\|9-(benzoyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho(2,1-c)pyran-7-carboxylic acid methyl ester\|methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-benzoyloxy-2-(furan-3-yl)-6a,10b-
Specifications & Purity	≥98%
Storage Temp	Store at 2-8°C,Desiccated
Shipped In	Wet ice
Product Description	Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets

OPRK1 Tclin Kappa-type opioid receptor 3 Activities

Discover Target: OPRK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRM1 Tclin Mu-type opioid receptor 4 Activities

Discover Target: OPRM1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-benzoyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
INCHI	InChI=1S/C28H30O8/c1-27-11-9-18-26(32)36-21(17-10-12-34-15-17)14-28(18,2)23(27)22(29)20(13-19(27)25(31)33-3)35-24(30)16-7-5-4-6-8-16/h4-8,10,12,15,18-21,23H,9,11,13-14H2,1-3H3/t18-,19-,20-,21-,23-,27-,28-/m0/s1
InChi Key	PYDQMXRFUVDCHC-XAGHGKQISA-N
Canonical SMILES	CC12CCC3C(=O)OC(CC3(C1C(=O)C(CC2C(=O)OC)OC(=O)C4=CC=CC=C4)C)C5=COC=C5
Isomeric SMILES	C[C@@]12CC[C@H]3C(=O)O[C@@H](C[C@@]3([C@H]1C(=O)[C@H](C[C@H]2C(=O)OC)OC(=O)C4=CC=CC=C4)C)C5=COC=C5
PubChem CID	11431898
Molecular Weight	494.53

References

1. Rowan MP et al.. (2014) Activation of mu opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) via ß-arrestin-2-mediated cross-talk.. PLoS One, 9 (4): (e93688). [PMID:24695785]
2. Casteels T et al.. (2021) An inhibitor-mediated beta-cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation.. Mol Metab, 54 (101329). [PMID:34454092]
3. Ji F et al.. (2013) Herkinorin dilates cerebral vessels via kappa opioid receptor and cyclic adenosine monophosphate (cAMP) in a piglet model.. Brain Res, 1490 (95-100). [PMID:23103502]
4. Cui X et al.. (2013) Ligand interaction, binding site and G protein activation of the mu opioid receptor.. Eur J Pharmacol, 702 (1-3): (309-15). [PMID:23415745]

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Herkinorin - ≥98%, high purity , CAS No.862073-77-6

Basic Description

Associated Targets

OPRK1 Tclin Kappa-type opioid receptor 3 Activities

OPRM1 Tclin Mu-type opioid receptor 4 Activities

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Related Documents

References

Solution Calculators

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Dilution Calculator

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