Click Here for 5% Off Your First Aladdin Purchase!

Hh-Ag1.5 - 10mM in DMSO, high purity , CAS No.612542-14-0(DMSO)

  • 10mM in DMSO
Item Number
H655961
Grouped product items
SKUSizeAvailabilityPrice Qty
H655961-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$528.90
View related series
Hedgehog Stem Cell/Wnt

Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Hh-Ag1.5 (SAg1.5) is a potent Hedgehog ( Hh ) agonist with an EC 50 of 1 nM Hh-Ag1.5 mediated reprogramming breaks the quiescence of noninjured liver stem cells for rescuing liver failure .

In Vitro

HhAg1.5 (5 μM; for 3 weeks) facilitates dramatic expansion of quiescent CD133 + CD45 - liver stem cells (Hh3A cells) enriched from non-injured liver in vitro. Hh-Ag1.5 competely binds to the Smo-containing membranes with the K i value of 0.52 nM. The Smo agonist SAG-1.5 displays nanomolar-range potency stimulation of Gli-responsive reporter activity, with an EC 50 of 7 nM . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:EC50: 1 nM (Hedgehog)

Names and Identifiers

Canonical SMILES CNC1CCC(CC1)N(CC2=CC(=CC=C2)C3=CC=NC=C3)C(=O)C4=C(C5=C(C=CC(=C5S4)F)F)Cl
Molecular Weight 526.04

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

Solution Calculators