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HPN , CAS No.H610857, Inhibitor of protein tyrosine phosphatase non-receptor type 1

HPN , CAS No.H610857, Inhibitor of protein tyrosine phosphatase non-receptor type 1

Item Number

H610857

Grouped product items
SKU	Size	Availability	Price	Qty
H610857-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$572.90
H610857-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of protein tyrosine phosphatase non-receptor type 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	3,4-dibromo-5-[[2-bromo-3,4-dihydroxy-6-(propan-2-yloxymethyl)phenyl]methyl]benzene-1,2-diol
INCHI	InChI=1S/C17H17Br3O5/c1-7(2)25-6-9-5-12(22)16(23)14(19)10(9)3-8-4-11(21)17(24)15(20)13(8)18/h4-5,7,21-24H,3,6H2,1-2H3
InChi Key	ZBDKXZCSKUHAPY-UHFFFAOYSA-N
Canonical SMILES	CC(OCc1cc(O)c(c(c1Cc1cc(O)c(c(c1Br)Br)O)Br)O)C
Isomeric SMILES	CC(C)OCC1=CC(=C(C(=C1CC2=CC(=C(C(=C2Br)Br)O)O)Br)O)O
PubChem CID	53371736

PubChem CID	53371736

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1. Shi D, Guo S, Jiang B, Guo C, Wang T, Zhang L, Li J. (2013) HPN, a synthetic analogue of bromophenol from red alga Rhodomela confervoides: synthesis and anti-diabetic effects in C57BL/KsJ-db/db mice.. Mar Drugs, 11 (2): (350-62). [PMID:23364683]
2. Luo J, Xu Q, Jiang B, Zhang R, Jia X, Li X, Wang L, Guo C, Wu N, Shi D. (2018) Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor.. Br J Pharmacol, 175 (1): (140-153). [PMID:29059712]

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