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HQL 79 - ≥99%(HPLC), high purity , CAS No.162641-16-9, Inhibitor of H-PGDS
Human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor
Basic Description Synonyms HQL-79|162641-16-9|HQL 79|4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE|4-benzhydryloxy-1-[3-(2H-tetrazol-5-yl)propyl]piperidine|1-(3-(1H-tetrazol-5-yl)propyl)-4-(benzhydryloxy)piperidine|CHEMBL574003|4-(diphenylmethoxy)-1-[3-(1h-tetrazol-5- Specifications & Purity Moligand™, ≥99%(HPLC) Biochemical and Physiological Mechanisms Orally active and specific inhibitor of human hematopoietic prostaglandin D synthase (H-PGDS) (IC50= 6μM). Antiallergic and anti-inflammatory; displays antiasthmatic activity and potent antihistaminic propertiesin vivo. Storage Temp Room temperature Shipped In Normal Grade Moligand™ Action Type INHIBITOR Mechanism of action Inhibitor of H-PGDS
Names and Identifiers IUPAC Name 4-benzhydryloxy-1-[3-(2H-tetrazol-5-yl)propyl]piperidine INCHI InChI=1S/C22H27N5O/c1-3-8-18(9-4-1)22(19-10-5-2-6-11-19)28-20-13-16-27(17-14-20)15-7-12-21-23-25-26-24-21/h1-6,8-11,20,22H,7,12-17H2,(H,23,24,25,26) InChi Key TZQGXAHOROZEKN-UHFFFAOYSA-N Canonical SMILES C1CN(CCC1OC(C2=CC=CC=C2)C3=CC=CC=C3)CCCC4=NNN=N4 Isomeric SMILES C1CN(CCC1OC(C2=CC=CC=C2)C3=CC=CC=C3)CCCC4=NNN=N4 PubChem CID 6540277 Molecular Weight 377.48
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 9.44, Max Conc. mM: 25
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