HSD-016 - 99%, high purity , CAS No.946396-92-5

  • ≥99%
Item Number
H648156
Grouped product items
SKUSizeAvailabilityPrice Qty
H648156-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$380.90
H648156-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$620.90
H648156-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,250.90
View related series
11β-HSD Metabolic Enzyme/Protease

Basic Description

Specifications & Purity≥99%
Biochemical and Physiological MechanismsHSD-016 is a potent, selective and orally active 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with IC 50 values of 11, 1 and 8 nM against human, mouse and rat 11β-HSD1, respectively. HSD-016 can be used for type 2 diabetes research.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

HSD-016 is a potent, selective and orally active 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with IC 50 values of 11, 1 and 8 nM against human, mouse and rat 11β-HSD1, respectively. HSD-016 can be used for type 2 diabetes research

Form:Solid

IC50& Target:IC 50 : 1 nM (mouse 11β-HSD1), 8 nM (rat 11β-HSD1), 11 nM (human 11β-HSD1)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Canonical SMILES C[C@@H]1CN(CCN1S(=O)(=O)C2=CC=CC(=C2)[C@](C)(C(F)(F)F)O)C3=C(C=C(C=C3)F)C(F)(F)F
Isomeric SMILES C[C@@H]1CN(CCN1S(=O)(=O)C2=CC=CC(=C2)[C@](C)(C(F)(F)F)O)C3=C(C=C(C=C3)F)C(F)(F)F
PubChem CID 16721125
Molecular Weight 514.46

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 100 mg/mL (194.38 mM; Need ultrasonic)

Related Documents

Solution Calculators