Basic Description

Specifications & Purity	≥ 300 IU/mg,from Streptomyces hyalurolyticus
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	EnzymoPure™
Product Description	Unit Definition One unit will cause a change in A600 of 0.330 per minute at pH 5.7 at 37°C in a 2.0 ml reaction mixture (45 minute assay).

Names and Identifiers

Enzyme Commission Number	4.2.2.1 (BRENDA, IUBMB)
Alternate CAS	37326-33-3

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot Number	Certificate Type	Date	Item
H2231488	Certificate of Analysis	Jul 29, 2022	H298749

FAQs and Articles

FAQ

Hyaluronan

Categories: Technical articles

Citations of This Product

1. Zhijun Zhang, Tiehong Yang, Jingwei Wang, Zhe Yu, Youbei Qiao, Chaoli Wang, Zhenggang Yue, Hong Wu. (2023) Hollow Mesoporous Molybdenum Single-Atom Nanozyme-Based Reactor for Enhanced Cascade Catalytic Antibacterial Therapy. International Journal of Nanomedicine, [PMID:38076729]
2. Junkai Jiang, Jialiang Xie, Liang Zhou, Wei Han, Jing Ye, Daorun Hu, Weichang Xie, Jianbin Qiu, Runfu Chen, Xiaolei Wang. (2023) Near infrared responsive nitric oxide and carbon monoxide nanoplatform for synergistic photodynamic therapy against periodontitis. CHEMICAL ENGINEERING JOURNAL, (21): (147850). [PMID:26134560]
3. Shaowei Pan, Zhaowei Yin, Chen Shi, Haonan Xiu, Guanfu Wu, Yongyuan Heng, Zhangyu Zhu, Jing Zhang, Jianchao Gui, Ziyi Yu, Bin Liang. (2023) Multifunctional Injectable Hydrogel Microparticles Loaded with miR-29a Abundant BMSCs Derived Exosomes Enhanced Bone Regeneration by Regulating Osteogenesis and Angiogenesis. Small, (15): (2306721). [PMID:38018340]
4. Zhaowei Yin, Chaoren Qin, Shaowei Pan, Chen Shi, Guanfu Wu, Yan Feng, Jing Zhang, Ziyi Yu, Bin Liang, Jianchao Gui. (2023) Injectable hyperbranched PEG crosslinked hyaluronan hydrogel microparticles containing mir-99a-3p modified subcutaneous ADSCs-derived exosomes was beneficial for long-term treatment of osteoarthritis. Materials Today Bio, 23 (100813). [PMID:37822452]
5. Pan Zejun, Hou Mingzhuang, Zhang Yijian, Liu Yang, Tian Xin, Hu Xiayu, Ge Xiaoyang, Zhao Zhijian, Liu Tao, Xu Yong, Yang Huilin, Liu Hao, Zhu Xuesong, He Fan. (2023) Incorporation of kartogenin and silk fibroin scaffolds promotes rat articular cartilage regeneration through enhancement of antioxidant functions. Regenerative Biomaterials, [PMID:37719927]
6. Songchao Duan, Fangfang Sun, Pan Qiao, Zhihui Zhu, Meilin Geng, Xiaobao Gong, Ying Li, Hanchun Yao. (2023) Detachable Dual-Targeting Nanoparticles for Improving the Antitumor Effect by Extracellular Matrix Depletion. ACS Biomaterials Science & Engineering, 9 (3): (1437–1449). [PMID:36795746]
7. Qiannan Li, Yufei Wang, Qianqian Zhu, Haifang Liu, Jianbo Liu, Hong-Min Meng, Zhaohui Li. (2023) A dual-mode system based on molybdophosphoric heteropoly acid and fluorescent microspheres for the reliable and ultrasensitive detection of alkaline phosphatase. ANALYST, 148 (6): (1259-1264). [PMID:36779364]
8. Chen Zhang, Zhengxiang Cheng, Yuanyuan Zhou, Ziyi Yu, Hongyu Mai, Changhao Xu, Jing Zhang, Jiali Wang. (2022) The novel hyaluronic acid granular hydrogel attenuates osteoarthritis progression by inhibiting the TLR-2/NF-κB signaling pathway through suppressing cellular senescence. Bioengineering & Translational Medicine, 8 (3): (e10475). [PMID:37206234]
9. Mengru Chen, Jiaqi Lu, Jun Hou, Yanbao Zhao, Lei Sun. (2022) Honeycomb-like porous silica nanoparticles for photo and chemo combination therapy. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 77 (103897). [PMID:]
10. Benbo Zhao, Mingda Zhao, Liming Li, Shixiong Sun, Heping Yu, Yuan Cheng, Yuedi Yang, Yujiang Fan, Yong Sun. (2022) Preparation and Properties of Double-Crosslinked Hydroxyapatite Composite Hydrogels. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (17): (9962). [PMID:36077353]
11. Sirui Han, Min Fan, Guichan Xu, Wenting Liu, Jingbo Chen, Yudong Lu, Shangyuan Feng, Ruiyun You. (2022) Gold-Nanostar-Based Surface-Enhanced Raman Scattering Substrates for Gastric Carcinoma Detection. ACS Applied Nano Materials, 5 (9): (12607–12615). [PMID:]
12. Siqi Ma, Zhaoqing Cong, Jiaxing Wei, Weiya Chen, Di Ge, Feifei Yang, Yonghong Liao. (2022) Pulmonary delivery of size-transformable nanoparticles improves tumor accumulation and penetration for chemo-sonodynamic combination therapy. JOURNAL OF CONTROLLED RELEASE, 350 (132). [PMID:35940360]
13. Zhao Xintong, Hua Yujie, Wang Tao, Ci Zheng, Zhang Yixin, Wang Xiaoyun, Lin Qiuning, Zhu Linyong, Zhou Guangdong. (2022) In vitro Cartilage Regeneration Regulated by a Hydrostatic Pressure Bioreactor Based on Hybrid Photocrosslinkable Hydrogels. Frontiers in Bioengineering and Biotechnology, 10 [PMID:35832408]
14. Bin Liu, Yulong Bian, Shuang Liang, Meng Yuan, Shuming Dong, Fei He, Shili Gai, Piaoping Yang, Ziyong Cheng, Jun Lin. (2022) One-Step Integration of Tumor Microenvironment-Responsive Calcium and Copper Peroxides Nanocomposite for Enhanced Chemodynamic/Ion-Interference Therapy. ACS Nano, 16 (1): (617–630). [PMID:34957819]

References

1. Zhijun Zhang, Tiehong Yang, Jingwei Wang, Zhe Yu, Youbei Qiao, Chaoli Wang, Zhenggang Yue, Hong Wu. (2023) Hollow Mesoporous Molybdenum Single-Atom Nanozyme-Based Reactor for Enhanced Cascade Catalytic Antibacterial Therapy. International Journal of Nanomedicine, [PMID:38076729]
2. Junkai Jiang, Jialiang Xie, Liang Zhou, Wei Han, Jing Ye, Daorun Hu, Weichang Xie, Jianbin Qiu, Runfu Chen, Xiaolei Wang. (2023) Near infrared responsive nitric oxide and carbon monoxide nanoplatform for synergistic photodynamic therapy against periodontitis. CHEMICAL ENGINEERING JOURNAL, (21): (147850). [PMID:26134560]
3. Shaowei Pan, Zhaowei Yin, Chen Shi, Haonan Xiu, Guanfu Wu, Yongyuan Heng, Zhangyu Zhu, Jing Zhang, Jianchao Gui, Ziyi Yu, Bin Liang. (2023) Multifunctional Injectable Hydrogel Microparticles Loaded with miR-29a Abundant BMSCs Derived Exosomes Enhanced Bone Regeneration by Regulating Osteogenesis and Angiogenesis. Small, (15): (2306721). [PMID:38018340]
4. Zhaowei Yin, Chaoren Qin, Shaowei Pan, Chen Shi, Guanfu Wu, Yan Feng, Jing Zhang, Ziyi Yu, Bin Liang, Jianchao Gui. (2023) Injectable hyperbranched PEG crosslinked hyaluronan hydrogel microparticles containing mir-99a-3p modified subcutaneous ADSCs-derived exosomes was beneficial for long-term treatment of osteoarthritis. Materials Today Bio, 23 (100813). [PMID:37822452]
5. Pan Zejun, Hou Mingzhuang, Zhang Yijian, Liu Yang, Tian Xin, Hu Xiayu, Ge Xiaoyang, Zhao Zhijian, Liu Tao, Xu Yong, Yang Huilin, Liu Hao, Zhu Xuesong, He Fan. (2023) Incorporation of kartogenin and silk fibroin scaffolds promotes rat articular cartilage regeneration through enhancement of antioxidant functions. Regenerative Biomaterials, [PMID:37719927]
6. Songchao Duan, Fangfang Sun, Pan Qiao, Zhihui Zhu, Meilin Geng, Xiaobao Gong, Ying Li, Hanchun Yao. (2023) Detachable Dual-Targeting Nanoparticles for Improving the Antitumor Effect by Extracellular Matrix Depletion. ACS Biomaterials Science & Engineering, 9 (3): (1437–1449). [PMID:36795746]
7. Qiannan Li, Yufei Wang, Qianqian Zhu, Haifang Liu, Jianbo Liu, Hong-Min Meng, Zhaohui Li. (2023) A dual-mode system based on molybdophosphoric heteropoly acid and fluorescent microspheres for the reliable and ultrasensitive detection of alkaline phosphatase. ANALYST, 148 (6): (1259-1264). [PMID:36779364]
8. Chen Zhang, Zhengxiang Cheng, Yuanyuan Zhou, Ziyi Yu, Hongyu Mai, Changhao Xu, Jing Zhang, Jiali Wang. (2022) The novel hyaluronic acid granular hydrogel attenuates osteoarthritis progression by inhibiting the TLR-2/NF-κB signaling pathway through suppressing cellular senescence. Bioengineering & Translational Medicine, 8 (3): (e10475). [PMID:37206234]
9. Mengru Chen, Jiaqi Lu, Jun Hou, Yanbao Zhao, Lei Sun. (2022) Honeycomb-like porous silica nanoparticles for photo and chemo combination therapy. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 77 (103897). [PMID:]
10. Benbo Zhao, Mingda Zhao, Liming Li, Shixiong Sun, Heping Yu, Yuan Cheng, Yuedi Yang, Yujiang Fan, Yong Sun. (2022) Preparation and Properties of Double-Crosslinked Hydroxyapatite Composite Hydrogels. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (17): (9962). [PMID:36077353]
11. Sirui Han, Min Fan, Guichan Xu, Wenting Liu, Jingbo Chen, Yudong Lu, Shangyuan Feng, Ruiyun You. (2022) Gold-Nanostar-Based Surface-Enhanced Raman Scattering Substrates for Gastric Carcinoma Detection. ACS Applied Nano Materials, 5 (9): (12607–12615). [PMID:]
12. Siqi Ma, Zhaoqing Cong, Jiaxing Wei, Weiya Chen, Di Ge, Feifei Yang, Yonghong Liao. (2022) Pulmonary delivery of size-transformable nanoparticles improves tumor accumulation and penetration for chemo-sonodynamic combination therapy. JOURNAL OF CONTROLLED RELEASE, 350 (132). [PMID:35940360]
13. Zhao Xintong, Hua Yujie, Wang Tao, Ci Zheng, Zhang Yixin, Wang Xiaoyun, Lin Qiuning, Zhu Linyong, Zhou Guangdong. (2022) In vitro Cartilage Regeneration Regulated by a Hydrostatic Pressure Bioreactor Based on Hybrid Photocrosslinkable Hydrogels. Frontiers in Bioengineering and Biotechnology, 10 [PMID:35832408]
14. Bin Liu, Yulong Bian, Shuang Liang, Meng Yuan, Shuming Dong, Fei He, Shili Gai, Piaoping Yang, Ziyong Cheng, Jun Lin. (2022) One-Step Integration of Tumor Microenvironment-Responsive Calcium and Copper Peroxides Nanocomposite for Enhanced Chemodynamic/Ion-Interference Therapy. ACS Nano, 16 (1): (617–630). [PMID:34957819]

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Hyaluronidase - ≥ 300 IU/mg,from Streptomyces hyalurolyticus, high purity , CAS No.37259-53-3