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Ibalizumab (anti-CD4) - Primary antibody, for ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt various applications, specific to CD4, >95%, high purity, Human IgG4SP, INHIBITOR of T-cell surface antigen CD4 inhibitor

  • Azide Free
  • Carrier Free
  • ExactAb™
  • Low Endotoxin
  • Recombinant
  • Validated
  • ≥95%(SDS-PAGE&SEC)
  • Lot by Lot
Features and benefits
  • Short Overview:

    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

  • Application: ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt
  • Species reactivity(Reacts with): Cynomolgus monkey,Human
  • Isotype: Human IgG4SP
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
Item Number
Ab170728
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab170728-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
Ab170728-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$987.90
Ab170728-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$2,517.90
Ab170728-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,987.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Accession#:P01730 CD4 Gene ID:920

Basic Description

Product NameIbalizumab (anti-CD4) - Primary antibody, for ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt various applications, specific to CD4, >95%, high purity, Human IgG4SP
SynonymsIbalizumab; TMB-355; TNX-355; CD 4 antibody; CD4 (L3T4) antibody; CD4 antibody; CD4 antigen (p55) antibody; CD4 antigen antibody; CD4 molecule antibody; CD4 receptor antibody; CD4+ Lymphocyte deficiency, included antibody; CD4_HUMAN antibody; CD4mut antib
Specifications & PurityExactAb™, Validated, Carrier Free, Low Endotoxin, Azide Free, Recombinant, ≥95%(SDS-PAGE&SEC), Lot by Lot
SpecificityCD4
ApplicationELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action TypeINHIBITOR
Mechanism of actionINHIBITOR of T-cell surface antigen CD4 inhibitor
Product Description

Ibalizumab (anti-CD4) is a humanised IgG4 monoclonal antibody that prevents HIV cell entry by binding to CD4 receptor. Ibalizumab (anti-CD4) has the potential for HIV-1 infection research. 


Purity

>95% (SDS-PAGE&SEC)

Endotoxin Level

< 1.0EU/mg


Product Properties

Antibody TypePrimary antibody
ClonalityRecombinant
IsotypeHuman IgG4SP
Light Chain Typekappa
SDS-PAGE147.36 kDa
Purification MethodProtein A purified
Purity>95%
SourceCHO supernatant
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -80°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS680188-33-4

Images

Ibalizumab (anti-CD4) (Ab170728) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD4 with Ibalizumab (anti-CD4) (Ab170728) (right panel) compared with Human IgG (Ab170213) - Isotype Control (left panel) and detected with Goat Anti-Human IgG (FITC) (Ab175834).

Ibalizumab (anti-CD4) (Ab170728) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD4 (red) with Ibalizumab (anti-CD4) (Ab170728) and detected with Goat Anti-Human IgG (FITC) (Ab175834). Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Ibalizumab (anti-CD4) (Ab170728) - SEC
The purity of Ibalizumab (anti-CD4) (Ab170728) is more than 95% verified by HPLC.

Associated Targets

CD4 Tclin T-cell surface glycoprotein CD4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
ZJ23F1001369Certificate of AnalysisOct 18, 2023 Ab170728
ZJ23F1001370Certificate of AnalysisOct 18, 2023 Ab170728

Related Documents

References

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27. Bernstein, Helene B HB and 5 more authors..  (2006)  CD4 expression on activated NK cells: ligation of CD4 induces cytokine expression and cell migration..  Journal of immunology (Baltimore, Md. : 1950),    (15):   [PMID:16951326]
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