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Ibufenac - ≥98%, high purity , Cyclooxygenase inhibitor, CAS No.1553-60-2, Cyclooxygenase inhibitor
Basic Description Synonyms Ibufenac|1553-60-2|4-Isobutylphenylacetic acid|Dytransin|Ibunac|2-(4-isobutylphenyl)acetic acid|Isodilan|Medirex|(p-Isobutylphenyl)acetic acid|Benzeneacetic acid, 4-(2-methylpropyl)-|(4-isobutylphenyl)acetic acid|4-(2-Methylpropyl)benzeneacetic acid|Ibufe Specifications & Purity ≥98% Biochemical and Physiological Mechanisms Ibufenac is a non-steroidal anti-inflammatory drug (NSAID) analog of ibuprofen that was withdrawn for hepatotoxicity. It inhibits cyclooxygenases COX-1 and -2 activity with IC50 values of 17.4 and 13.1 μM, respectively and > 40 μM for 5-LOX. It has been u Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Action Type INHIBITOR Mechanism of action Cyclooxygenase inhibitor Product Description Ibufenac (Dytransin) is an analog of Ibuprofen. Ibuprofen is a non-steroidal anti-rheumatoid agen and non-selective COX inhibitor used to research mild-moderate pain, fever, and inflammation.
Names and Identifiers IUPAC Name 2-[4-(2-methylpropyl)phenyl]acetic acid INCHI InChI=1S/C12H16O2/c1-9(2)7-10-3-5-11(6-4-10)8-12(13)14/h3-6,9H,7-8H2,1-2H3,(H,13,14) InChi Key CYWFCPPBTWOZSF-UHFFFAOYSA-N Canonical SMILES CC(C)CC1=CC=C(C=C1)CC(=O)O Isomeric SMILES CC(C)CC1=CC=C(C=C1)CC(=O)O RTECS AI4200000 PubChem CID 15250 Molecular Weight 192.25
Chemical and Physical Properties Solubility DMSO: 20 mg/mL, clear Sensitivity Moisture sensitive
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
RTECS AI4200000
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