Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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I129291-25g | 25g | In stock | $9.90 | |
I129291-100g | 100g | In stock | $14.90 | |
I129291-250g | 250g | Available within 1-2 weeks(?) Item is derived from our semi-finished stock and is processed in 1-2 weeks. | $32.90 | |
I129291-500g | 500g | In stock | $57.90 |
A nonsteroidal anti-inflammatory drug (NSAID). COX inhibitor.
Synonyms | ibuprofen|15687-27-1|2-(4-Isobutylphenyl)propanoic acid|Motrin|Brufen|Advil|Nurofen|Dolgit|Liptan|Medipren|Nuprin|Anflagen|Buburone|Butylenin|Ibuprocin|Lamidon|Ebufac|Ibumetin|Mynosedin|Roidenin|Andran|Apsifen|Bluton|Epobron|Haltran|Nobfen|Nobgen|Trendar| |
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Specifications & Purity | Moligand™, ≥98%(GC) |
Biochemical and Physiological Mechanisms | Cyclooxygenase (COX) inhibitor that has greater activity against COX-1 than against COX-2.A nonsteroidal anti-inflammatory drug (NSAID). Non-selective inhibitor of COX-1 and COX-2 (IC 50 values are 12 and 80 µM respectively). Inhibits thromboxane B2 relea |
Shipped In | Normal |
Grade | Moligand™ |
Action Type | AGONIST, CHANNEL BLOCKER, INHIBITOR |
Mechanism of action | Channel blocker of ASIC1;Inhibitor of COX-1;Inhibitor of COX-2;Agonist of Peroxisome proliferator-activated receptor-γ;Inhibitor of SMCT1 |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description |
Ibuprofen is a commonly used nonsteroidal anti-inflammatory drug (NSAID) known for its pain-relieving, anti-inflammatory, and fever-reducing properties. It can hinder the effectiveness of various antihypertensive medications, including β-adrenergic blockers, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and diuretics. Ibuprofen exists in an unbound state in cerebrospinal fluid and is accumulated in the synovial fluid of inflamed joints in arthritis patients.
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ALogP | 3.5 |
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Pubchem Sid | 488179781 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179781 |
IUPAC Name | 2-[4-(2-methylpropyl)phenyl]propanoic acid |
INCHI | InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) |
InChi Key | HEFNNWSXXWATRW-UHFFFAOYSA-N |
Canonical SMILES | CC(C)CC1=CC=C(C=C1)C(C)C(=O)O |
Isomeric SMILES | CC(C)CC1=CC=C(C=C1)C(C)C(=O)O |
WGK Germany | 3 |
RTECS | MU6640000 |
Alternate CAS | 31121-93-4 |
PubChem CID | 3672 |
Molecular Weight | 206.28 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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F2421551 | Certificate of Analysis | Jun 07, 2024 | I129291 |
F2421552 | Certificate of Analysis | Jun 07, 2024 | I129291 |
F2421556 | Certificate of Analysis | Jun 07, 2024 | I129291 |
F2421560 | Certificate of Analysis | Jun 07, 2024 | I129291 |
F2421559 | Certificate of Analysis | Jun 07, 2024 | I129291 |
F2421558 | Certificate of Analysis | Jun 07, 2024 | I129291 |
F2421557 | Certificate of Analysis | Jun 07, 2024 | I129291 |
C2414620 | Certificate of Analysis | Mar 02, 2024 | I129291 |
C2414621 | Certificate of Analysis | Mar 02, 2024 | I129291 |
C2414628 | Certificate of Analysis | Mar 02, 2024 | I129291 |
C2226255 | Certificate of Analysis | Jan 05, 2024 | I129291 |
K2328447 | Certificate of Analysis | Nov 17, 2023 | I129291 |
K2328454 | Certificate of Analysis | Nov 17, 2023 | I129291 |
D2422081 | Certificate of Analysis | Nov 17, 2023 | I129291 |
K2328488 | Certificate of Analysis | Nov 17, 2023 | I129291 |
K2328489 | Certificate of Analysis | Nov 17, 2023 | I129291 |
D2403057 | Certificate of Analysis | Nov 17, 2023 | I129291 |
C2304666 | Certificate of Analysis | Feb 15, 2023 | I129291 |
C2304786 | Certificate of Analysis | Feb 15, 2023 | I129291 |
C2304507 | Certificate of Analysis | Feb 15, 2023 | I129291 |
C2304497 | Certificate of Analysis | Feb 15, 2023 | I129291 |
C2304505 | Certificate of Analysis | Feb 15, 2023 | I129291 |
C2304504 | Certificate of Analysis | Feb 15, 2023 | I129291 |
C2304498 | Certificate of Analysis | Feb 15, 2023 | I129291 |
A2303380 | Certificate of Analysis | Jan 07, 2023 | I129291 |
A2303391 | Certificate of Analysis | Jan 07, 2023 | I129291 |
A2107092 | Certificate of Analysis | Oct 24, 2022 | I129291 |
D2422082 | Certificate of Analysis | Aug 24, 2022 | I129291 |
I2304094 | Certificate of Analysis | Aug 24, 2022 | I129291 |
J2210526 | Certificate of Analysis | Aug 24, 2022 | I129291 |
J2210527 | Certificate of Analysis | Aug 24, 2022 | I129291 |
J2210528 | Certificate of Analysis | Aug 24, 2022 | I129291 |
J2210529 | Certificate of Analysis | Aug 24, 2022 | I129291 |
J2210530 | Certificate of Analysis | Aug 24, 2022 | I129291 |
C2226265 | Certificate of Analysis | Feb 25, 2022 | I129291 |
C2226243 | Certificate of Analysis | Feb 25, 2022 | I129291 |
C2226297 | Certificate of Analysis | Feb 25, 2022 | I129291 |
C2226306 | Certificate of Analysis | Feb 25, 2022 | I129291 |
A2219177 | Certificate of Analysis | Feb 14, 2022 | I129291 |
Solubility | Soluble in ethanol (25 mg/ml), chloroform (1:1), ether (1:2), acetone (1:1.5), aqueous solutions of alkali hydroxides and carbonates, dichloromethane, methanol (50 mg/ml), and ethyl acetate. Insoluble in water. |
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Boil Point(°C) | 157°C/4mmHg |
Melt Point(°C) | 75-78℃ |
Pictogram(s) | GHS08, GHS07 |
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Signal | Warning |
Hazard Statements | H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | MU6640000 |
Merck Index | 4881 |
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