IC 87201 - 95%, high purity , CAS No.866927-10-8

  • ≥95%
Item Number
I286663
Grouped product items
SKUSizeAvailabilityPrice Qty
I286663-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$161.90
I286663-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$268.90
I286663-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,210.90
I286663-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,178.90

nNOS-PSD95 protein-protein interaction inhibitor; also antinociceptive and antidepressant

Basic Description

Specifications & Purity≥95%
Biochemical and Physiological MechanismsIC87201 is a potent inhibitor of the nNOS/PSD-95 protein-protein interaction that blocks NMDA-induced 3′ ,5′ -cyclic guanosine monophosphate (cGMP) production in hippocampal cultures. IC87201 exhibits analgesic properties in mice pain models. Contrary to
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

IC87201, an inhibitor of PSD95-nNOS protein-protein interactions, suppresses NMDAR-dependent NO and cGMP formation.

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 2-[(2H-benzotriazol-5-ylamino)methyl]-4,6-dichlorophenol
INCHI InChI=1S/C13H10Cl2N4O/c14-8-3-7(13(20)10(15)4-8)6-16-9-1-2-11-12(5-9)18-19-17-11/h1-5,16,20H,6H2,(H,17,18,19)
InChi Key QEHVTUCLCBXQIC-UHFFFAOYSA-N
Canonical SMILES C1=CC2=NNN=C2C=C1NCC3=C(C(=CC(=C3)Cl)Cl)O
Isomeric SMILES C1=CC2=NNN=C2C=C1NCC3=C(C(=CC(=C3)Cl)Cl)O
PubChem CID 11771269
Molecular Weight 309.15

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityThe highest concentration (mg/ml): 28, the highest concentration (mm): 100; Soluble in ethanol, maximum concentration (mg/ml): none, maximum concentration (mm): 100

Safety and Hazards(GHS)

RIDADR NONHforallmodesoftransport

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