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Icariin - analytical standard,≥98%, high purity , CAS No.489-32-7

  • analytical standard
  • ≥98%
Item Number
I107343
Grouped product items
SKUSizeAvailabilityPrice Qty
I107343-20mg
20mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$83.90
View related series
Natural glycosides

Basic Description

SynonymsIcariin|489-32-7|Ieariline|5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-
Specifications & Purityanalytical standard, ≥98%
Biochemical and Physiological MechanismsFlavonoid glucoside derived from plants of the genus Epimedium. The pharmacologically active ingredient or its derivative can promote bone formation, regulate multi-drug resistance, enhance neuronal activity, stimulate angiogenesis, and exhibit antioxidan
Storage TempStore at 2-8°C
Shipped InWet ice
Gradeanalytical standard
Product Description

General description:

Icariin is a major flavonoid isolated from Epimedium spp. leaves, used as a traditional Chinese medicine to nourish the kidney and reinforce yang.


application:

Icariin has been used as a test material to investigate its, in vitro effect in promoting mouse hair follicle growth, which is assessed by vibrissae hair follicle (VHF) organ-culture model.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Associated Targets

POLB Tchem DNA polymerase beta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PDE5A Tclin cGMP-specific 3',5'-cyclic phosphodiesterase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PDE6C Tclin Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KDM1A Tchem Lysine-specific histone demethylase 1A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one
INCHI InChI=1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1
InChi Key TZJALUIVHRYQQB-XLRXWWTNSA-N
Canonical SMILES COc1ccc(cc1)C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(=O)c4c(O)cc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(C\C=C(\C)C)c4O2
Isomeric SMILES C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O
WGK Germany 3
PubChem CID 5318997
Molecular Weight 676.66

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
E2409236Certificate of AnalysisApr 23, 2024 I107343
E2409237Certificate of AnalysisApr 23, 2024 I107343
E2409238Certificate of AnalysisApr 23, 2024 I107343
C2204418Certificate of AnalysisDec 14, 2023 I107343
A2403392Certificate of AnalysisDec 13, 2023 I107343
A2403402Certificate of AnalysisDec 13, 2023 I107343
C2204417Certificate of AnalysisDec 11, 2021 I107343
C2204422Certificate of AnalysisDec 11, 2021 I107343
C2204423Certificate of AnalysisDec 11, 2021 I107343
C2204491Certificate of AnalysisDec 11, 2021 I107343

Chemical and Physical Properties

Specific Rotation[α]-84° (C=1,Pyridine)
Melt Point(°C)235 - 239°C

Safety and Hazards(GHS)

WGK Germany 3
Merck Index 3617

Related Documents

Solution Calculators