Click Here for 5% Off Your First Aladdin Purchase!
Call +1 (833) 552-7181 or Contact us Earn $25 in coupons on your first order with Aladdin!
Toggle Nav
My Cart
Search
Advanced Search
Menu
Sign In
྾
main product photo

ICI 118551 , CAS No.72795-26-7, Antagonist of β 2-adrenoceptor;Antagonist of β 3-adrenoceptor

  • Moligand™
Item Number
I610921
Grouped product items
SKUSizeAvailabilityPrice Qty
I610921-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
I610921-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90
Add to Wish List Compare
Bulk Order  SDS  DATASHEET
View related series
β2-adrenoceptor Antagonist β3-adrenoceptor Antagonist

Basic Description

SynonymsICI-118,551;ICI-118551
Specifications & PurityMoligand™
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of β 2-adrenoceptor;Antagonist of β 3-adrenoceptor

Associated Targets

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRB2 Tclin Beta-2 adrenergic receptor 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRB3 Tclin Beta-3 adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (2S,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol
INCHI InChI=1S/C17H27NO2/c1-11(2)18-13(4)16(19)10-20-17-9-8-12(3)14-6-5-7-15(14)17/h8-9,11,13,16,18-19H,5-7,10H2,1-4H3/t13-,16+/m0/s1
InChi Key VFIDUCMKNJIJTO-XJKSGUPXSA-N
Canonical SMILES Cc1c2CCCc2c(cc1)OC[C@H]([C@H](C)NC(C)C)O
Isomeric SMILES CC1=C2CCCC2=C(C=C1)OC[C@H]([C@H](C)NC(C)C)O
PubChem CID 5311179

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

 SDS

 Specification Sheet

References

1. Baker JR, Hothersall JD, Fitzmaurice RJ, Tucknott M, Vinter A, Tinker A, Caddick S.  (2010)  An efficient asymmetric synthesis of the potent beta-blocker ICI-118,551 allows the determination of enantiomer dependency on biological activity..  Chem Commun (Camb),  46  (22): (3953-4).  [PMID:20431838]

Solution Calculators

Privacy Policy Website Terms of Use Return policy Terms and Conditions of Sale Cookie Policy Sales Policy
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2023-present Aladdin Scientific Corp . All rights reserved.