ICI 192,605 - ≥96%, high purity , CAS No.117621-64-4, Antagonist of TP receptor

Item Number

I342536

Grouped product items
SKU	Size	Availability	Price	Qty
I342536-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$85.90
I342536-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$327.90

a potent thromboxane A2 receptor antagonist

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Basic Description

Synonyms	117621-64-4\|ICI 192605\|6-(2-(2-Chlorophenyl-4-hydroxyphenyl)-1,3-dioxan-5-yl)hexenoic acid\|Ici-192605\|(Z)-6-[(2R,4R,5S)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hex-4-enoic acid\|ICI 192,605\|FQ9418XA31\|4-Hexenoic acid, 6-(2-(2-chlorophenyl)-4
Specifications & Purity	≥96%
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of TP receptor
Product Description	ICI 192,605 is a cell signaling prostaglandin that has been shown to be a potent TXA2R (thromboxane A2 receptor) antagonist. ICI 192,605 competitively inhibits contractile responces to U-46619 .

Names and Identifiers

IUPAC Name	(Z)-6-[(2R,4R,5S)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hex-4-enoic acid
INCHI	InChI=1S/C22H23ClO5/c23-18-11-6-4-9-16(18)22-27-14-15(8-2-1-3-13-20(25)26)21(28-22)17-10-5-7-12-19(17)24/h1-2,4-7,9-12,15,21-22,24H,3,8,13-14H2,(H,25,26)/b2-1-/t15-,21+,22+/m0/s1
InChi Key	WHUIENZXNGAHQI-YGPRPMEGSA-N
Canonical SMILES	C1C(C(OC(O1)C2=CC=CC=C2Cl)C3=CC=CC=C3O)CC=CCCC(=O)O
Isomeric SMILES	C1[C@@H]([C@@H](O[C@@H](O1)C2=CC=CC=C2Cl)C3=CC=CC=C3O)C/C=C\CCC(=O)O
WGK Germany	3
PubChem CID	6438399
UN Number	3077
Packing Group	III
Molecular Weight	402.87

CAS Registry No.

PubChem CID

GPCRdb Ligand

Safety and Hazards(GHS)

Pictogram(s)	GHS09, GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects
Precautionary Statements	P273:Avoid release to the environment. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P391:Collect spillage. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.
WGK Germany	3
Class	9
RIDADR	UN30779/PGIII

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Basic Description