Idarubicin HCl - ≥98%, high purity , DNA topoisomerase II alpha inhibitor, CAS No.57852-57-0, DNA topoisomerase II alpha inhibitor

Item Number

I129863

Grouped product items
SKU	Size	Availability	Price
I129863-1mg	1mg	In stock	$16.90
I129863-5mg	5mg	In stock	$68.90
I129863-10mg	10mg	In stock	$117.90
I129863-50mg	50mg	In stock	$395.90

Basic Description

Synonyms	idarubicin hydrochloride\|Idarubicin Hcl\|57852-57-0\|Idamycin\|Zavedos\|Idarubicin (hydrochloride)\|Idamycin PFS\|IMI 30\|UNII-5VV3MDU5IE\|5VV3MDU5IE\|Idarubicin hydrochloride PFS\|IMI-30\|DTXSID0047797\|4-Demethoxydaunorubicin hydrochloride\|EINECS 260-990-7\|Idarubic
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Dry ice
Action Type	INHIBITOR
Mechanism of action	DNA topoisomerase II alpha inhibitor
Product Description	Idarubicin HCl is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL. An apoptosis inducer.

Names and Identifiers

Pubchem Sid	488190836
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488190836
IUPAC Name	(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride
INCHI	InChI=1S/C26H27NO9.ClH/c1-10-21(29)15(27)7-17(35-10)36-16-9-26(34,11(2)28)8-14-18(16)25(33)20-19(24(14)32)22(30)12-5-3-4-6-13(12)23(20)31;/h3-6,10,15-17,21,29,32-34H,7-9,27H2,1-2H3;1H/t10-,15-,16-,17-,21+,26-;/m0./s1
InChi Key	JVHPTYWUBOQMBP-RVFAQHLVSA-N
Canonical SMILES	CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O.Cl
Isomeric SMILES	C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O.Cl
WGK Germany	3
RTECS	HB7877000
PubChem CID	636362
Molecular Weight	533.95

Certificates

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11 results found

Lot Number	Certificate Type	Date	Item
G2319744	Certificate of Analysis	Jun 26, 2023	I129863
G2319768	Certificate of Analysis	Jun 26, 2023	I129863
E2308840	Certificate of Analysis	Jan 30, 2023	I129863
E2308856	Certificate of Analysis	Jan 30, 2023	I129863
E2308862	Certificate of Analysis	Jan 30, 2023	I129863
E2308866	Certificate of Analysis	Jan 30, 2023	I129863
E2308872	Certificate of Analysis	Jan 30, 2023	I129863
E2308876	Certificate of Analysis	Jan 30, 2023	I129863
E2308878	Certificate of Analysis	Jan 30, 2023	I129863
E2308922	Certificate of Analysis	Jan 30, 2023	I129863
B2217085	Certificate of Analysis	Feb 21, 2022	I129863

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08
Signal	Danger
Hazard Statements	H341:Suspected of causing genetic defects H351:Suspected of causing cancer H300:Fatal if swallowed H360:May damage fertility or the unborn child
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P281:Use personal protective equipment as required. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice.
WGK Germany	3
RTECS	HB7877000

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Basic Description