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STE:Homologs of yeast Sterile 7, Sterile 11, Sterile 20 kinases
Il-94 , CAS No.I611016, Inhibitor of p21 (RAC1) activated kinase 1;Inhibitor of p21 (RAC1) activated kinase 2

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Il-94 , CAS No.I611016, Inhibitor of p21 (RAC1) activated kinase 1;Inhibitor of p21 (RAC1) activated kinase 2

Moligand™

PubChem CID: 73348907

Item Number

I611016

Grouped product items
SKU	Size	Availability	Price	Qty
I611016-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
I611016-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

p21 (RAC1) activated kinase 1 Inhibitor p21 (RAC1) activated kinase 2 Inhibitor

Basic Description

Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of p21 (RAC1) activated kinase 1;Inhibitor of p21 (RAC1) activated kinase 2

Associated Targets

PAK1 Tchem Serine/threonine-protein kinase PAK 1 1 Activities

Discover Target: PAK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PAK2 Tchem Serine/threonine-protein kinase PAK 2 1 Activities

Discover Target: PAK2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PAK3 Tchem Serine/threonine-protein kinase PAK 3 0 Activities

Discover Target: PAK3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-N-[(6-fluoro-1H-indazol-4-yl)methyl]-2-N-(2-methoxyethyl)pyrimidine-2,4-diamine
INCHI	InChI=1S/C21H23FN8O/c1-31-7-6-30(12-14-8-15(22)9-18-16(14)11-24-27-18)21-23-5-4-19(26-21)25-20-10-17(28-29-20)13-2-3-13/h4-5,8-11,13H,2-3,6-7,12H2,1H3,(H,24,27)(H2,23,25,26,28,29)
InChi Key	FTGUWURNNBVUBC-UHFFFAOYSA-N
Canonical SMILES	COCCN(c1nccc(n1)Nc1n[nH]c(c1)C1CC1)Cc1cc(F)cc2c1cn[nH]2
Isomeric SMILES	COCCN(CC1=C2C=NNC2=CC(=C1)F)C3=NC=CC(=N3)NC4=NNC(=C4)C5CC5
PubChem CID	73348907

Database links

ChEMBL Ligand	CHEMBL2386715
PubChem CID	73348907

Certificates

Certificate of Analysis(COA)

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References

1. Abdel-Magid AF. (2013) PAK1: A Therapeutic Target for Cancer Treatment.. ACS Med Chem Lett, 4 (5): (431-2). [PMID:24900689]

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