mAb (C1); Mouse anti Human IL10RB Antibody; WB; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab109838-10μl | 10μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $89.90 | |
| Ab109838-20μl | 20μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $129.90 | |
| Ab109838-50μl | 50μl | In stock | $269.90 | |
| Ab109838-100μl | 100μl | In stock | $399.90 | |
| Ab109838-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,999.90 |
mAb (C1); Mouse anti Human IL10RB Antibody; WB; Unconjugated
| Product Name | IL10RB Mouse mAb - Primary antibody, specific to IL10RB, Mouse IgG1 |
|---|---|
| Synonyms | CDw210b antigen; CDw210b; CRF2-4IL-10R subunit 2; CRFB4; CRFB4human transmembrane receptor protein; cytokine receptor10CDW210B; D21S58; D21S66; IBD25; IL-10 R beta; IL-10 receptor subunit beta; IL10R beta; IL-10R2; IL-10R2IL-10R subunit beta; IL10RB; IL-1 |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, Azide Free, High performance, Lot by Lot |
| Host species | Mouse |
| Specificity | IL10RB |
| Immunogen | Recombinant IL-10RB expressed in E.coli (AA 87-243) |
| Positive Control | WB: HeLa, Jurkat, HEK293, NIH/3T3 and C6 cell lysates. |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, High performance, Validated |
| Product Description | Mouse anti Human IFNGR1 Antibody, Monoclonal (C3), could be used for WB and so on. Application: WB: 0.01-2µg/mL Protein Function Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IL29. |
| Isotype | Mouse IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A + Protein G purified |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
IL10RB Mouse mAb (Ab109838) - Western Blot
All lanes: IL10RB Mouse mAb (Ab109838) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab130840) at 1/20000 dilution
Predicted band size: 37 kDa
Observed band size: 58 kDa
Exposure time: 19.3 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB |
0.01-2 µg/mL
|
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ23F1101855 | Certificate of Analysis | Nov 29, 2023 | Ab109838 |
| ZJ23F1101856 | Certificate of Analysis | Nov 29, 2023 | Ab109838 |
| 1. Stefanich EG, Rae J, Sukumaran S, Lutman J, Lekkerkerker A, Ouyang W, Wang X, Lee D, Danilenko DM, Diehl L et al.. (2018) Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases.. Biochem Pharmacol, 152 (3): (224-235). [PMID:29608910] |
| 2. Sharon Gauci,Andreas O Helbig,Monique Slijper,Jeroen Krijgsveld,Albert J R Heck,Shabaz Mohammed. (2009-05-06) Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.. Analytical chemistry, 81 ((11)): (4493-4501). [PMID:19413330] |
| 3. Lutfalla, G G, McInnis, M G MG, Antonarakis, S E SE and Uzé, G G.. (1995) Structure of the human CRFB4 gene: comparison with its IFNAR neighbor.. Journal of molecular evolution, [PMID:7563119] |
| 4. Lutfalla, G G, Gardiner, K K and Uzé, G G.. (1993) A new member of the cytokine receptor gene family maps on chromosome 21 at less than 35 kb from IFNAR.. Genomics, [PMID:8314576] |
| 5. Kotenko, S V SV and 5 more authors.. (1997) Identification and functional characterization of a second chain of the interleukin-10 receptor complex.. The EMBO journal, (1): [PMID:9312047] |
| 6. Xie, M H MH and 8 more authors.. (2000) Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R.. The Journal of biological chemistry, (6): [PMID:10875937] |
| 7. Sheppard, Paul P and 25 more authors.. (2003) IL-28, IL-29 and their class II cytokine receptor IL-28R.. Nature immunology, [PMID:12469119] |
| 8. Donnelly, Raymond P RP, Sheikh, Faruk F, Kotenko, Sergei V SV and Dickensheets, Harold H.. (2004) The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain.. Journal of leukocyte biology, [PMID:15123776] |
| 9. Zhang, Zemin Z and Henzel, William J WJ.. (2004) Signal peptide prediction based on analysis of experimentally verified cleavage sites.. Protein science : a publication of the Protein Society, [PMID:15340161] |
| 10. Frodsham, Angela J AJ and 16 more authors.. (2006) Class II cytokine receptor gene cluster is a major locus for hepatitis B persistence.. Proceedings of the National Academy of Sciences of the United States of America, (13): [PMID:16757563] |
| 11. Glocker, Erik-Oliver EO and 27 more authors.. (2009) Inflammatory bowel disease and mutations affecting the interleukin-10 receptor.. The New England journal of medicine, (19): [PMID:19890111] |
| 12. Yoon, Sung-Il SI and 8 more authors.. (2010) Structure and mechanism of receptor sharing by the IL-10R2 common chain.. Structure (London, England : 1993), (12): [PMID:20462497] |
