mAb (C6); Mouse anti Human IL22 Antibody; WB; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab110155-10μl | 10μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $49.90 | |
| Ab110155-20μl | 20μl | In stock | $99.90 | |
| Ab110155-50μl | 50μl | In stock | $149.90 | |
| Ab110155-100μl | 100μl | In stock | $219.90 | |
| Ab110155-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,079.90 |
mAb (C6); Mouse anti Human IL22 Antibody; WB; Unconjugated
| Product Name | IL22 Mouse mAb - Primary antibody, specific to IL22, Mouse IgG2a |
|---|---|
| Synonyms | Cytokine Zcyto18; IL-10-related T-cell-derived inducible factor; IL22; IL-22; IL-D110; IL-TIF; ILTIFIL-10-related T-cell-derived-inducible factor; IL-TIFMGC79382; interleukin 22; interleukin-22; MGC79384; TIFa; TIFIL-23; zcyto18; Cytokine Zcyto18 antibody |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, Azide Free, High performance, Lot by Lot |
| Host species | Mouse |
| Specificity | IL22 |
| Immunogen | Recombinant IL22 expressed in E.coli (AA 34-179) |
| Positive Control | WB: CTLL-2, MOLT-4, Jurkat, HeLa, NIH/3T3 and C6 cell lysates. |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, Validated, 高性能 |
| Product Description | Mouse anti Human IL22 Antibody, Monoclonal (C6), could be used for WB and so on. Application: WB: 0.01-2µg/mL Protein Function Cytokine that contributes to the inflammatory response in vivo. |
| Isotype | Mouse IgG2a |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A + Protein G purified |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
IL22 Mouse mAb (Ab110155) - Western Blot
All lanes: IL22 Mouse mAb (Ab110155) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution
Predicted band size: 20 kDa
Observed band size: 14 kDa
Exposure time: 9.9 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB |
0.01-2 µg/mL
|
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ23F1201975 | Certificate of Analysis | Dec 13, 2023 | Ab110155 |
| ZJ23F1201976 | Certificate of Analysis | Dec 13, 2023 | Ab110155 |
| ZJ23F1201977 | Certificate of Analysis | Dec 13, 2023 | Ab110155 |
| 1. Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C et al.. (2003) The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.. Genome Res, 13 (10): (2265-70). [PMID:12975309] |
| 2. Xie, M H MH and 8 more authors.. (2000) Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R.. The Journal of biological chemistry, (6): [PMID:10875937] |
| 3. Dumoutier, L L, Van Roost, E E, Colau, D D and Renauld, J C JC.. (2000) Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor.. Proceedings of the National Academy of Sciences of the United States of America, (29): [PMID:10954742] |
| 4. Dumoutier, L L, Van Roost, E E, Ameye, G G, Michaux, L L and Renauld, J C JC.. (2000) IL-TIF/IL-22: genomic organization and mapping of the human and mouse genes.. Genes and immunity, [PMID:11197690] |
| 5. Nagem, R A P RA and 5 more authors.. (2002) Crystallization and synchrotron X-ray diffraction studies of human interleukin-22.. Acta crystallographica. Section D, Biological crystallography, [PMID:11856845] |
| 6. Zhang, Zemin Z and Henzel, William J WJ.. (2004) Signal peptide prediction based on analysis of experimentally verified cleavage sites.. Protein science : a publication of the Protein Society, [PMID:15340161] |
| 7. Brand, Stephan S and 14 more authors.. (2007) IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro.. American journal of physiology. Gastrointestinal and liver physiology, [PMID:17204547] |
| 8. Jones, Brandi C BC, Logsdon, Naomi J NJ and Walter, Mark R MR.. (2008) Structure of IL-22 bound to its high-affinity IL-22R1 chain.. Structure (London, England : 1993), (10): [PMID:18599299] |
| 9. Akil, Hussein H and 12 more authors.. (2015) IL22/IL-22R pathway induces cell survival in human glioblastoma cells.. PloS one, [PMID:25793261] |
| 10. Moniruzzaman, Md M, Wang, Ran R, Jeet, Varinder V, McGuckin, Michael A MA and Hasnain, Sumaira Z SZ.. (2019) Interleukin (IL)-22 from IL-20 Subfamily of Cytokines Induces Colonic Epithelial Cell Proliferation Predominantly through ERK1/2 Pathway.. International journal of molecular sciences, (15): [PMID:31311100] |
