pAb; Rabbit anti Human IL22RA1 Antibody; WB; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab110168-10μl | 10μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $76.90 | |
| Ab110168-50μl | 50μl | In stock | $229.90 | |
| Ab110168-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $379.90 | |
| Ab110168-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,399.90 |
pAb; Rabbit anti Human IL22RA1 Antibody; WB; Unconjugated
| Product Name | IL22RA1 Antibody - Primary antibody, specific to IL22RA1, Rabbit IgG |
|---|---|
| Synonyms | CRF2-9; CRF2-9interleukin 22 receptor; Cytokine receptor class-II member 9; Cytokine receptor family 2 member 9; IL-22 R alpha 1; IL-22 receptor subunit alpha-1; IL22R alpha 1; IL22R; IL22R1; IL22RA1; IL-22Ra1; IL-22R-alpha-1; IL-TIF-R1; interleukin 22 re |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, 0.5 mg/mL |
| Host species | Rabbit |
| Specificity | IL22RA1 |
| Immunogen | A KLH conjugated synthetic peptide from the C-terminal region of human IL22RA1 (AA 408-436) |
| Positive Control | WB: K562, Hep G2, HEK293 and NIH/3T3 cell lysates. |
| Conjugation | Unconjugated |
| Grade | Carrier Free, ExactAb™, Validated |
| Product Description |
Rabbit anti Human IL22RA1 Antibody, Polyclonal, could be used for WB and so on. |
| Isotype | Rabbit IgG |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified + Peptide affinity purified |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
IL22RA1 Antibody (Ab110168) - Western Blot
All lanes: IL22RA1 Antibody (Ab110168) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 63 kDa
Observed band size: 75 kDa
Exposure time: 56.8 s
IL22RA1 Antibody (Ab110168) - Western Blot
All lanes: IL22RA1 Antibody (Ab110168) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 63 kDa
Observed band size: 75 kDa
Exposure time: 7.2 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB |
1/1000
|
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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ23F1202134 | Certificate of Analysis | Dec 20, 2023 | Ab110168 |
| ZJ23F1202133 | Certificate of Analysis | Dec 20, 2023 | Ab110168 |
| 1. Stefanich EG, Rae J, Sukumaran S, Lutman J, Lekkerkerker A, Ouyang W, Wang X, Lee D, Danilenko DM, Diehl L et al.. (2018) Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases.. Biochem Pharmacol, 152 (3): (224-235). [PMID:29608910] |
| 2. Xie, M H MH and 8 more authors.. (2000) Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R.. The Journal of biological chemistry, (6): [PMID:10875937] |
| 3. Kotenko, S V SV and 6 more authors.. (2001) Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta ) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes.. The Journal of biological chemistry, (26): [PMID:11035029] |
| 4. Dumoutier, L L, Leemans, C C, Lejeune, D D, Kotenko, S V SV and Renauld, J C JC.. (2001) Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:11564763] |
| 5. Wang, Mai M, Tan, Zhongjia Z, Zhang, Rong R, Kotenko, Sergei V SV and Liang, Peng P.. (2002) Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2.. The Journal of biological chemistry, (1): [PMID:11706020] |
| 6. Parrish-Novak, Julia J and 12 more authors.. (2002) Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions.. The Journal of biological chemistry, (6): [PMID:12351624] |
| 7. Ramesh, Rajagopal R and 14 more authors.. (2003) Melanoma differentiation-associated gene 7/interleukin (IL)-24 is a novel ligand that regulates angiogenesis via the IL-22 receptor.. Cancer research, (15): [PMID:12941841] |
| 8. Li, Jing J and 19 more authors.. (2004) Temporal associations between interleukin 22 and the extracellular domains of IL-22R and IL-10R2.. International immunopharmacology, [PMID:15120653] |
| 9. Gregory, S G SG and 178 more authors.. (2006) The DNA sequence and biological annotation of human chromosome 1.. Nature, (18): [PMID:16710414] |
| 10. Brand, Stephan S and 14 more authors.. (2007) IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro.. American journal of physiology. Gastrointestinal and liver physiology, [PMID:17204547] |
| 11. Kebir, Hania H and 9 more authors.. (2007) Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation.. Nature medicine, [PMID:17828272] |
| 12. Boniface, K K and 11 more authors.. (2007) A role for T cell-derived interleukin 22 in psoriatic skin inflammation.. Clinical and experimental immunology, [PMID:17900301] |
| 13. Ramanathan, Murugappan M, Spannhake, Ernst W EW and Lane, Andrew P AP.. (2007) Chronic rhinosinusitis with nasal polyps is associated with decreased expression of mucosal interleukin 22 receptor.. The Laryngoscope, [PMID:17906500] |
| 14. Kragstrup, Tue Wenzel TW and 6 more authors.. (2008) The expression of IL-20 and IL-24 and their shared receptors are increased in rheumatoid arthritis and spondyloarthropathy.. Cytokine, [PMID:18061474] |
| 15. Bleicher, Lucas L and 6 more authors.. (2008) Crystal structure of the IL-22/IL-22R1 complex and its implications for the IL-22 signaling mechanism.. FEBS letters, (3): [PMID:18675809] |
