| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| I422117-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $69.90 |
Proton Pump Inhibitors
| Synonyms | Ilaprazole sodium | Sodium ilaprazole | 172152-50-0 | Ilaprazole (sodium) | T8KRT8S6GR | Ilaprazole sodium [WHO-DD] | Sodiumilaprazole | sodium;2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-5-pyrrol-1-ylbenzimidazol-3-ide | 1H-Benzimidazole, 2-(((4-methoxy-3-methyl- |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Ilaprazole (IY-81149) sodium is the sodium salt form of ilaprazole, which is a proton pump inhibitor. Ilaprazole sodium irreversibly inhibits H(+)/K(+)-ATPase in a dose-dependent manner with IC50 of 6 μM in rabbit parietal cell preparation. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Information Ilaprazole sodium Ilaprazole (IY-81149) sodium is the sodium salt form of ilaprazole, which is a proton pump inhibitor. Ilaprazole sodium irreversibly inhibits H(+)/K(+)-ATPase in a dose-dependent manner with IC50 of 6 μM in rabbit parietal cell preparation. Targets Proton pump ; H(+)/K(+)-ATPase (in rabbit parietal cell preparation) ; 6 μM |
| ALogP | 3.414 |
|---|---|
| Rotatable Bond | 5 |
| IUPAC Name | sodium;2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-5-pyrrol-1-ylbenzimidazol-3-ide |
|---|---|
| INCHI | InChI=1S/C19H17N4O2S.Na/c1-13-17(20-8-7-18(13)25-2)12-26(24)19-21-15-6-5-14(11-16(15)22-19)23-9-3-4-10-23;/h3-11H,12H2,1-2H3;/q-1;+1 |
| InChi Key | ZQGDDMFDBZPGCD-UHFFFAOYSA-N |
| Canonical SMILES | CC1=C(C=CN=C1CS(=O)C2=NC3=C([N-]2)C=C(C=C3)N4C=CC=C4)OC.[Na+] |
| Isomeric SMILES | CC1=C(C=CN=C1CS(=O)C2=NC3=C([N-]2)C=C(C=C3)N4C=CC=C4)OC.[Na+] |
| PubChem CID | 121595900 |
| Molecular Weight | 388.42 |
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| DMSO(mg / mL) Max Solubility | 78 |
|---|---|
| DMSO(mM) Max Solubility | 200.81355234025 |
| Water(mg / mL) Max Solubility | -1 |
