ILK-IN-3 - 99%, high purity , CAS No.6975-75-3

Item Number

I649033

• Synonyms: 6975-75-3|ILK-IN-3|4-((4-Methoxyphenyl)diazenyl)-1H-pyrazole-3,5-diamine|4-[(4-methoxyphenyl)hydrazono]-4h-pyrazole-3,5-diamine|QLT0267|866409-68-9|MLS000737992|4-[(4-methoxyphenyl)diazenyl]-1H-pyrazole-3,5-diamine|4-(4-Methoxy-phenylazo)-1H-pyrazole-3,5-
• Specifications & Purity: 99%
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads

Product Description

ILK-IN-3 is an orally active integrin linked kinase (ILK) inhibitor. ILK-IN-3 improves the anticancer efficacy of Docetaxel ( HY-B0011 ) in orthotopic LCC6 model.

In Vitro

ILK-IN-3 (compound 4, 10 μM) inhibits DYRK1, GSK3α/β, CDK5/p25 kinase activity to 17%, 51%, 47%, 95%, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

ILK-IN-3 (QLT0267) (200 mg/kg，口服，28 天) 抑制原位 LCC6 模型中的肿瘤生长 。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid