IgG4 antibodies will dominate the IgG response in schistosomiasis, lymphatic filariasis, and in patients after allergen immunotherapy. Unlike the other IgG subclasses, IgG4 does not activate complement. A combined IgA-IgG4 deficiency has been associated with recurrent pyogenic infections. Prepared from myeloma plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests
Specifications & Purity
≥95%(SDS-PAGE), Extinction Coefficient: 1.36
Predicted molecular weight
146,000Da
Product Specifications
Form
Frozen in 20 mM phosphate, pH 7.4, with 150 mM NaCl and 0.05% NaN3.
