Reconstitute with 1.0 M acetic acid to the pre-lyophilization volume. Dilutions must be made in Acetic Acid. IgM heavy chain (mu chain) consists of 576 amino acids; there are five mu chains in each IgM molecule. IgM heavy chain is purified by reducing the disulfide bond connecting it to the IgM kappa and lambda light chains. IgM mu chain is more highly conserved across different species than is the heavy chain of IgG or IgA. Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests. Ref: Hayzer, D. J., and Jaton, J-C. 1985. Methods Enzymol. 116, 16; Jeske, D. J., and Capra J. D. 1984. Fundamental Immunology (W.E. Paul, ed.), 131.