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Impentamine dihydrobromide , CAS No.34973-91-6, Agonist of H 3 receptor;Antagonist of H 3 receptor
a selective H3 receptor antagonist
Basic Description Synonyms Impentamine|34973-91-6|1H-Imidazole-4-pentanamine|5-(1H-imidazol-5-yl)pentan-1-amine|PDSP1_000940|PDSP2_000926|4-(5-aminopentyl)imidazole|88JSL4TQ76|VUF-4702|UNII-88JSL4TQ76|CHEMBL417096|GTPL1252|SCHEMBL7860359|SCHEMBL9221066|BDBM22908|DTXSID70430734|5-(1 Specifications & Purity Moligand™ Storage Temp Room temperature,Desiccated Shipped In Normal Grade Moligand™ Action Type AGONIST, ANTAGONIST Mechanism of action Agonist of H 3 receptor;Antagonist of H 3 receptor Product Description Impentamine dihydrobromide is a selective H|3|receptor antagonist. This compound displays >30000-fold selectivity over H|1|and H|2|receptors. In SK-N-MC cells expressing human H|3|receptors, this can act as a partial agonist. Impentamine dihydrobromide also displays antinociceptive properties, possibly via a non-H|1|-H|2|or -H|3|receptor-mediated mechanism.
Names and Identifiers IUPAC Name 5-(1H-imidazol-5-yl)pentan-1-amine INCHI InChI=1S/C8H15N3/c9-5-3-1-2-4-8-6-10-7-11-8/h6-7H,1-5,9H2,(H,10,11) InChi Key MZCJWLAXZRFUPI-UHFFFAOYSA-N Canonical SMILES C1=C(NC=N1)CCCCCN Isomeric SMILES C1=C(NC=N1)CCCCCN PubChem CID 9793868 Molecular Weight 315.05
Chemical and Physical Properties Solubility Soluble to 100 mM in Water and to 100 mM in DMSO
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