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INCB-38579 , CAS No.I611057, Antagonist of H 1 receptor;Antagonist of H 2 receptor;Antagonist of H 3 receptor;Antagonist of H 4 receptor

  • Moligand™
Item Number
I611057
Grouped product items
SKUSizeAvailabilityPrice Qty
I611057-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
I611057-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90

Basic Description

GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of H 1 receptor;Antagonist of H 2 receptor;Antagonist of H 3 receptor;Antagonist of H 4 receptor

Associated Targets

HRH4 Tchem Histamine H4 receptor 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HRH3 Tclin Histamine H3 receptor 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HRH2 Tclin Histamine H2 receptor 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HRH1 Tclin Histamine H1 receptor 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 1-{7-[2-amino-6-(4-methylpiperazin-1-yl)-1,2-dihydropyrimidin-4-yl]-1,2,3,4-tetrahydroisoquinolin-2-yl}-3-cyclopentylpropan-1-one
INCHI InChI=1S/C26H38N6O/c1-30-12-14-31(15-13-30)24-17-23(28-26(27)29-24)21-8-7-20-10-11-32(18-22(20)16-21)25(33)9-6-19-4-2-3-5-19/h7-8,16-17,19,26,29H,2-6,9-15,18,27H2,1H3
InChi Key JZAGLPUCLXBELH-UHFFFAOYSA-N
Canonical SMILES CN1CCN(CC1)C1=CC(=NC(N1)N)c1ccc2c(c1)CN(CC2)C(=O)CCC1CCCC1
Isomeric SMILES CN1CCN(CC1)C2=NC(NC(=C2)C3=CC4=C(CCN(C4)C(=O)CCC5CCCC5)C=C3)N
PubChem CID 117072554

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