Integrin alpha 4/CD49D Rat mA - Primary antibody, specific to Integrin alpha 4/CD49D, Rat IgG2b
Specifications & Purity
Validated, Azide Free, Carrier Free, ≥95%(SDS-PAGE), Lot by Lot
Host species
Rat
Specificity
Integrin alpha 4/CD49D
Immunogen
Mouse P815 mast cells
Conjugation
Unconjugated
Grade
Azide Free, Carrier Free, Validated
Product Description
Rat anti Mouse/Human Integrin alpha 4/CD49D Antibody, Monoclonal (PS/2), could be used for Flow, in vivo VLA-4 neutralization, in vitro VLA-4 neutralization and so on. Application: Flow: Use at an assay dependent concentration. in vivo VLA-4 neutralization: Use at an assay dependent concentration. in vitro VLA-4 neutralization: Use at an assay dependent concentration. Protein Function Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
Product Properties
Isotype
Rat IgG2b
Light Chain Type
kappa
SDS-PAGE
150 kDa
Purification Method
Protein G purified
Form
Liquid
Concentration
Lot by Lot
Storage Temp
Store at 2-8°C,Freeze prohibited
Shipped In
Wet ice
Stability And Storage
Shipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon delivery aliquot.
Images
Integrin alpha 4/CD49D Rat mAb (Ab110790) - Flow Cytometry Flow Cytometry analysis of human peripheral blood lymphocytes labelling Integrin alpha 4/CD49D with Integrin alpha 4/CD49D Rat mAb (Ab110790) conjugated with biotin (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Rat IgG Isotype Control Antibody (Biotin) (Ab180310) (left panel) and detected with SA-PE (rp156150).
Integrin alpha 4/CD49D Rat mAb (Ab110790) - Flow Cytometry Flow Cytometry analysis of human peripheral blood lymphocytes labelling Integrin alpha 4/CD49D (red) with Integrin alpha 4/CD49D Rat mAb (Ab110790) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Rat IgG Isotype Control Antibody (Biotin) (Ab180310). Black - Unlabelled control, cells without incubation with primary antibody.