Click Here for 5% Off Your First Aladdin Purchase!

Integrin beta 7 Rat mAb - Primary antibody, specific to Integrin beta 7, Rat IgG2a

  • Azide Free
  • Carrier Free
  • Validated
  • ≥95%(SDS-PAGE)
  • Lot by Lot
Features and benefits
  • Short Overview:

    mAb (FIB504); Rat anti Human/Mouse Integrin beta 7 Antibody; Flow, IP, WB, in vivo blocking of integrin β7; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse
  • Isotype: Rat IgG2a
    Application:
  • Animal Model
  • Blocking
  • Flow Cytometry
  • Functional Assay
  • IP
  • WB
Item Number
Ab110906
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab110906-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$29.90
Ab110906-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab110906-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$99.90
Ab110906-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$229.90

mAb (FIB504); Rat anti Human/Mouse Integrin beta 7 Antibody; Flow, IP, WB, in vivo blocking of integrin β7; Unconjugated

Basic Description

Product NameIntegrin beta 7 Rat mAb - Primary antibody, specific to Integrin beta 7, Rat IgG2a
Specifications & PurityValidated, Azide Free, Carrier Free, ≥95%(SDS-PAGE), Lot by Lot
Host speciesRat
SpecificityIntegrin beta 7
ImmunogenTK1 cells
ConjugationUnconjugated
GradeAzide Free, Carrier Free, Validated
Product Description

Rat anti Human/Mouse Integrin beta 7 Antibody, Monoclonal (FIB504), could be used for Flow, IP, WB, in vivo blocking of integrin β7 and so on.

Application

Flow: Use at an assay dependent concentration.

IP: Use at an assay dependent concentration.

WB: Use at an assay dependent concentration.

in vivo blocking of integrin β7: Use at an assay dependent concentration.
Protein Function
Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.

Product Properties

IsotypeRat IgG2a
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein G purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at 2-8°C,Freeze prohibited
Shipped InWet ice
Stability And StorageShipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon delivery aliquot.

Associated Targets

ITGB7 Tclin Integrin beta-7 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

Use at an assay dependent concentration.

IP

Use at an assay dependent concentration.

Flow

Use at an assay dependent concentration.

in vivo blocking of integrin β7

Use at an assay dependent concentration

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0607439Certificate of AnalysisJun 26, 2024 Ab110906
ZJ24F0607438Certificate of AnalysisJun 26, 2024 Ab110906
ZJ24F0607437Certificate of AnalysisJun 26, 2024 Ab110906

Related Documents

Solution Calculators