Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab183425-100μg | 100μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $89.90 | |
| Ab183425-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $449.90 | |
| Ab183425-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,129.90 | |
| Ab183425-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,809.90 |
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Intetumumab (anti-ITGAV) - Primary antibody, specific to ITGAV, Human IgG1 |
|---|---|
| Specifications & Purity | ExactAb™, Validated, Carrier Free, Low Endotoxin, Azide Free, Recombinant, ≥95%(SDS-PAGE&SEC), Lot by Lot |
| Specificity | ITGAV |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | ANTAGONIST |
| Mechanism of action | ANTAGONIST of Integrin alpha-V/beta-3 antagonist |
| Product Description | Intetumumab (anti-ITGAV) is a potent anti-EGFR monoclonal antibody that is glycoengineered for enhanced antibody-dependent cellular cytotoxicity (ADCC). Intetumumab (anti-ITGAV) can be used in research of cancer. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145.14 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
| CAS | 725735-28-4 |
Intetumumab (anti-ITGAV) (Ab183425) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling ITGAV (red) with Intetumumab (anti-ITGAV) (Ab183425). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Intetumumab (anti-ITGAV) (Ab183425) - SEC
The purity of Intetumumab (anti-ITGAV) (Ab183425) is more than 95% verified by HPLC.
Intetumumab (anti-ITGAV) (Ab183425) - Flow Cytometry
Flow Cytometry analysis of A549 cells labelling ITGAV (red) with Intetumumab (anti-ITGAV) (Ab183425). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Intetumumab (anti-ITGAV) (Ab183425) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling ITGAV (red) with Intetumumab (anti-ITGAV) (Ab183425). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Intetumumab (anti-ITGAV) (Ab183425) - Flow Cytometry
Flow Cytometry analysis of HT-29 cells labelling ITGAV (red) with Intetumumab (anti-ITGAV) (Ab183425). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Intetumumab (anti-ITGAV) (Ab183425) - Flow Cytometry
Flow Cytometry analysis of HUVEC cells labelling ITGAV (red) with Intetumumab (anti-ITGAV) (Ab183425). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0607001 | Certificate of Analysis | Jun 19, 2024 | Ab183425 |
| ZJ24F0607000 | Certificate of Analysis | Jun 19, 2024 | Ab183425 |
| ZJ24F0606999 | Certificate of Analysis | Jun 19, 2024 | Ab183425 |
