| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| I275346-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $90.90 |
Cell-permeable STAT5 inhibitor
| Synonyms | N2-11H-Indolo[3,2-c]quinolin-6-yl-N1,N1-dimethyl-1,2-ethanediamine |
|---|---|
| Specifications & Purity | ≥98% |
| Storage Temp | Store at 2-8°C |
| Shipped In | Wet ice |
| IUPAC Name | N-(11H-indolo[3,2-c]quinolin-6-yl)-N',N'-dimethylethane-1,2-diamine |
|---|---|
| INCHI | InChI=1S/C19H20N4/c1-23(2)12-11-20-19-17-13-7-3-5-9-15(13)21-18(17)14-8-4-6-10-16(14)22-19/h3-10,21H,11-12H2,1-2H3,(H,20,22) |
| InChi Key | UROLFQZUYMCOHV-UHFFFAOYSA-N |
| Canonical SMILES | CN(C)CCNC1=NC2=CC=CC=C2C3=C1C4=CC=CC=C4N3 |
| Isomeric SMILES | CN(C)CCNC1=NC2=CC=CC=C2C3=C1C4=CC=CC=C4N3 |
| PubChem CID | 24204050 |
| Molecular Weight | 304.39 |
Enter Lot Number to search for COA:
| Solubility | Soluble in DMSO to 100 mM and in ethanol to 100 mM |
|---|
| 1. Itcho K et al.. (2019) Angiotensin 1-7 suppresses angiotensin II mediated aldosterone production via JAK/STAT signaling inhibition.. J Steroid Biochem Mol Biol, 185 (137-141). [PMID:30125658] |
| 2. Moyama C et al.. (2022) Stat5b inhibition blocks proliferation and tumorigenicity of glioblastoma stem cells derived from a de novo murine brain cancer model.. Am J Cancer Res, 12 (3): (1129-1142). [PMID:35411230] |
| 3. Sami E et al.. (2020) The Immunosuppressive Microenvironment in BRCA1-IRIS-Overexpressing TNBC Tumors Is Induced by Bidirectional Interaction with Tumor-Associated Macrophages.. Cancer Res, 80 (5): (1102-1117). [PMID:31911557] |
